Journal ArticleDOI
Ca2+ ion cross-linked interpenetrating network matrix tablets of polyacrylamide-grafted-sodium alginate and sodium alginate for sustained release of diltiazem hydrochloride
TLDR
In this article, an interpenetrating network (IPN) matrix tablet of diltiazem-HCl (DTZ) was prepared by wet granulation method using polyacrylamide-grafted-sodium alginate (PAam-g-SAL) co-polymer and sodium alginates (SAL), for sustained release of the drug.About:
This article is published in Carbohydrate Polymers.The article was published on 2010-10-15. It has received 91 citations till now. The article focuses on the topics: Calcium alginate & Drug carrier.read more
Citations
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Journal ArticleDOI
Alginate derivatization: a review of chemistry, properties and applications.
Siddhesh N. Pawar,Kevin J. Edgar +1 more
TL;DR: Progress towards controlled synthesis of alginate derivatives, and the properties and applications of these derivatives are reviewed.
Journal ArticleDOI
Synthesis, characterization, swelling and drug release behavior of semi-interpenetrating network hydrogels of sodium alginate and polyacrylamide
TL;DR: Solution pH, crosslinker concentration and monomer to SA weight ratio of the hydrogels were found to have a strong effect on adsorption and in vitro release profile of the drug from the gel matrix.
Journal ArticleDOI
Alginate drug delivery systems: application in context of pharmaceutical and biomedical research
TL;DR: Worldwide researchers are exploring possible applications of alginates as coating material, preparation of controlled-release drug delivery systems such as microspheres, beads, pellets, gels, fibers, membranes, etc.
Journal ArticleDOI
Marine Origin Polysaccharides in Drug Delivery Systems
TL;DR: Marine polysaccharides have important biological properties such as biocompatibility, biodegradability, and anti-inflammatory activity, as well as adhesive and antimicrobial actions and have been studied as raw material for the construction of carrier devices for drugs, including particles, capsules and hydrogels.
Journal ArticleDOI
Interpenetrating polymer networks as innovative drug delivery systems.
TL;DR: The present review encompassesIPNs, their types, method of synthesis, factors which affects the morphology of IPNs, extensively studied IPN based drug delivery systems, and some natural polymers widely used for IPNs.
References
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Journal ArticleDOI
A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Alginate in drug delivery systems.
TL;DR: The present use and future possibilities of alginate as a tool in drug formulation are discussed, with the potential use of the various qualities as pharmaceutical excipients likely to make an important contribution in the development of polymeric delivery systems.
Journal ArticleDOI
Thermoresponsive hydrogels in biomedical applications.
Leda Klouda,Antonios G. Mikos +1 more
TL;DR: The scope of this paper is to review the aqueous polymer solutions that exhibit transition to gel upon temperature change and focuses mainly on hydrogels based on natural polymers as well as poly(ethylene glycol)-biodegradable polyester copolymers.
Book
Novel Drug Delivery Systems
TL;DR: Concepts and System Design for the Rate-Controlled Drug Delivery Fundamentals of Rate-Control Drug Delivery Oral Drug Delivery and Delivery Systems Mucosal Drug Delivery: Potential Routes for Noninvasive Systemic Administration and Regulatory Considerations in Controlled Drug Delivery.