Cancer of the Esophagus and Esophagogastric Junction: An Eighth Edition Staging Primer.
TLDR
This primer for eighth edition staging of esophageal and esophagogastric epithelial cancers presents separate classifications for the clinical, pathologic, and postneoadjuvant pathologic stage groups, which are no longer shared.About:
This article is published in Journal of Thoracic Oncology.The article was published on 2017-01-01 and is currently open access. It has received 356 citations till now. The article focuses on the topics: Esophageal cancer & Adenocarcinoma.read more
Citations
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Retrospective study: The diagnostic accuracy of conventional forceps biopsy of gastric epithelial compared to endoscopic submucosal dissection (STROBE compliant).
TL;DR: According to the analysis, old men plus gastric fundus or antrum of CFB were strongly suggested to perform ESD if precancerous lesions were found and young women with low-grade intraepithelial neoplasia could select regular follow-up.
Journal ArticleDOI
Comparative Molecular Analyses of Esophageal Squamous Cell Carcinoma, Esophageal Adenocarcinoma, and Gastric Adenocarcinoma
Mohamed E. Salem,Alberto Puccini,Joanne Xiu,Derek Raghavan,Heinz-Josef Lenz,W. Michael Korn,Anthony F. Shields,Philip A. Philip,John L. Marshall,Richard M. Goldberg +9 more
TL;DR: The genomic heterogeneity of gastroesophageal cancers is highlighted, showing striking molecular differences between tumors originating from different locations, supporting the fact that adenocarcinomas and squamous cell carcinomas are completely different diseases, irrespective of the tumor location.
Journal ArticleDOI
Preoperative pembrolizumab combined with chemoradiotherapy for oesophageal squamous cell carcinoma (PALACE-1).
Chengqiang Li,Shengguang Zhao,Yuyan Zheng,Yichao Han,Xiaoyan Chen,Zenghui Cheng,Yuquan Wu,Xi-Jia Feng,Weixiang Qi,Kai Chen,Jie Xiang,Jian Li,Toni Lerut,Hecheng Li +13 more
TL;DR: In this article, the safety and activity of preoperative pembrolizumab combined with chemoradiotherapy for resectable oesophageal squamous cell carcinoma (ESCC) were investigated.
Journal ArticleDOI
Esophagectomy With Three-Field Versus Two-Field Lymphadenectomy for Middle and Lower Thoracic Esophageal Cancer: Long-Term Outcomes of a Randomized Clinical Trial
Bin Li,Yawei Zhang,Longsheng Miao,Longfei Ma,Xiaoyang Luo,Yiliang Zhang,Ting Ye,Hecheng Li,Jie Zhang,Yuan Li,Kuaile Zhao,Min Fan,Zhengfei Zhu,Jialei Wang,Jie Xu,Youjia Deng,Qiong Lu,Hang Li,Yang Zhang,Yunjian Pan,Shilei Liu,Longlong Shao,Yihua Sun,Jiaqing Xiang,Hong Hu,Haiquan Chen +25 more
TL;DR: For patients with middle and lower thoracic esophageal cancer, there was no improvement in OS or DFS after esophagectomy with three-field lymphadenectomy over two-fieldymphadenectomy.
Journal ArticleDOI
Robotic-assisted Esophagectomy vs Video-Assisted Thoracoscopic Esophagectomy (REVATE): study protocol for a randomized controlled trial.
Yin-Kai Chao,Zhi-Gang Li,Yu-Wen Wen,Dae Joon Kim,Seong Yong Park,Yu-Ling Chang,Pieter C. van der Sluis,Jelle P. Ruurda,Richard van Hillegersberg +8 more
TL;DR: The REVATE study provides an opportunity to explore whether RE could facilitate LND along the left RLN—a complex surgical procedure that, as of now and with the use of VATE, remains difficult to perform and associated with a significant burden of morbidity.
References
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Journal ArticleDOI
Recommendations for neoadjuvant pathologic staging (ypTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals.
Thomas W. Rice,Hemant Ishwaran,Wayne L. Hofstetter,David P. Kelsen,Carolyn Apperson-Hansen,Eugene H. Blackstone +5 more
TL;DR: Analytical and consensus processes that produced recommendations for pathologic stage groups (pTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition are reported.
Book ChapterDOI
Esophagus and Esophagogastric Junction
Carolyn C. Compton,David R. Byrd,Julio Garcia-Aguilar,Scott H. Kurtzman,Alexander B. Olawaiye,Mary Kay Washington +5 more
TL;DR: Tumor location is simplified, and esophagogastric junction and proximal 5 cm of stomach are included, and Tis is redefined and T4 is subclassified Regional lymph nodes are redefined.
Journal ArticleDOI
Worldwide esophageal cancer collaboration: clinical staging data
Thomas W. Rice,Carolyn Apperson-Hansen,L. M. DiPaola,M. E. Semple,T. Lerut,Mark B. Orringer,Chen Lq,Wayne L. Hofstetter,B. M. Smithers,Valerie W. Rusch,B. P. L. Wijnhoven,K. N. Chen,Andrew Davies,Xavier Benoit D’Journo,Kenneth A. Kesler,James D. Luketich,Mark K. Ferguson,Jari Räsänen,R. van Hillegersberg,W Fang,L. Durand,William H. Allum,Ivan Cecconello,Robert J. Cerfolio,M. Pera,S. M. Griffin,Renate Burger,Jun-Feng Liu,Mark S. Allen,Simon Law,Thomas J. Watson,Gail Darling,Walter J. Scott,A. Duranceau,Chadrick E. Denlinger,Paul H. Schipper,Hemant Ishwaran,Eugene H. Blackstone +37 more
TL;DR: Patients with early cancers had worse survival and those with advanced cancers better survival than expected from equivalent pathologic categories based on prior WECC pathologic data, making clinically based treatment decisions difficult and pre-treatment prognostication inaccurate.
Journal ArticleDOI
Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?
TL;DR: It is timely to review the current understanding of OAC and intestinal-type GC, integrating advances from cell-of-origin studies and comprehensive genomic alteration analyses, ultimately enabling better insight into the relationship between these two cancers.
Journal ArticleDOI
Recommendations for neoadjuvant pathologic staging (ypTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals: Esophageal cancer staging recommendations: neoadjuvant pathologic
Thomas W. Rice,Hemant Ishwaran,David P. Kelsen,Wayne L. Hofstetter,Carolyn Apperson-Hansen,Eugene H. Blackstone +5 more
TL;DR: Analytical and consensus processes that produced recommendations for neoadjuvant pathologic stage groups (ypTNM) of esophageal and esophagogastric junction cancer for the AJCC/UICC cancer staging manuals, 8th edition are reported.
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