Journal ArticleDOI
Carbocycles from donor–acceptor cyclopropanes
TLDR
This review summarizes research directed towards the formation of carbocyclic adducts from donor-acceptor cyclopropanes and focuses on annulation and cycloaddition reactions mediated by Lewis or protic acid, bases, or thermal conditions.Abstract:
This review summarizes research directed towards the formation of carbocyclic adducts from donor–acceptor cyclopropanes. The focus of the review is on annulation and cycloaddition reactions (both inter- and intramolecularly) mediated by Lewis or protic acid, bases, or thermal conditions. Rearrangements resulting in carbocycles and those reactions mediated by transition metal catalysis have been excluded.read more
Citations
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Synthesis of 1‐Substituted Pyrazolines by Reaction of Donor‐Acceptor Cyclopropanes with 1,5‐Diazabicyclo[3.1.0]hexanes
Alexey O. Chagarovskiy,V. Kuznetsov,Olga A. Ivanova,Olga A. Ivanova,Alexander S. Goloveshkin,Irina I. Levina,Nina N. Makhova,Igor V. Trushkov +7 more
Journal ArticleDOI
Electrocatalytic Activation of Donor-Acceptor Cyclopropanes and Cyclobutanes: An Alternative C(sp3 )-C(sp3 ) Cleavage Mode.
TL;DR: In this paper, the first electrochemical activation of cyclopropanes and cyclobutanes leading after C(sp3)−C(sp 3) cleavage to the formation of highly reactive radical cations was described.
Journal ArticleDOI
Nickel-Catalyzed Asymmetric Domino Ring Opening/Cross-Coupling Reaction of Cyclobutanones via a Reductive Strategy
TL;DR: The preliminary mechanistic investigations support a mechanism involving Ni(I)-mediated enantiotopic C−C σ-bond activation of cyclobutanones as key elementary step in the catalytic cycle.
Journal ArticleDOI
The Bonding and Reactivity of α-Carbonyl Cyclopropanes
TL;DR: In this article, the authors present the different facets of cyclopropane bonding by examining the main models that have been used to explain the reactivity of the functionality over the years.
Journal ArticleDOI
Regioselective Hydrogenolysis of Donor–Acceptor Cyclopropanes with Zn-AcOH Reductive System
Konstantin L. Ivanov,Elena V. Villemson,Gennadij V. Latyshev,Stanislav I. Bezzubov,Alexander G. Majouga,Alexander G. Majouga,Mikhail Ya. Melnikov,Ekaterina M. Budynina +7 more
TL;DR: A convenient low-cost method for regioselective ring-opening of donor-acceptor cyclopropanes with the Zn-AcOH reductive system was developed and the utility of the synthesized compounds was demonstrated by transforming them into valuable acyclic and cyclic compounds.
References
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Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events
Koon K. Teo,Janice Pogue,Leanne Dyal,Ingrid Copland,Helmut Schumacher,Gilles R. Dagenais,Craig S. Anderson +6 more
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A new golden age for donor-acceptor cyclopropanes.
TL;DR: This Review highlights the appropriate tools for successfully employing donor-acceptor cyclopropanes in ring-opening reactions, cycloadditions, and rearrangements.
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