Journal ArticleDOI
Carbocycles from donor–acceptor cyclopropanes
TLDR
This review summarizes research directed towards the formation of carbocyclic adducts from donor-acceptor cyclopropanes and focuses on annulation and cycloaddition reactions mediated by Lewis or protic acid, bases, or thermal conditions.Abstract:
This review summarizes research directed towards the formation of carbocyclic adducts from donor–acceptor cyclopropanes. The focus of the review is on annulation and cycloaddition reactions (both inter- and intramolecularly) mediated by Lewis or protic acid, bases, or thermal conditions. Rearrangements resulting in carbocycles and those reactions mediated by transition metal catalysis have been excluded.read more
Citations
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Journal ArticleDOI
Organocatalytic activation of cyclopropanes in asymmetric synthesis
TL;DR: In this article , a review of different reactions developed in this field in which different organocatalytic activation manifolds have been employed to trigger the ring opening event is presented.
Journal ArticleDOI
Cascade Ring-Opening/Cyclization Reaction of Spiro(nitrocyclopropane)oxindoles with Huisgen Zwitterions and Synthesis of Pyrazolo[3,4-b]indoles.
TL;DR: In this article , a ring-opening/cyclization cascade reaction of spiro(nitrocyclopropane)oxindoles with in situ generated Huisgen zwitterions (HZs) from PPh3 and azodicarboxylates was reported.
Journal ArticleDOI
Asymmetric (5 + 3) Annulation of Donor–Acceptor Cyclopropanes with Imidazolidines: Access to Saturated 1,4-Diazocanes
TL;DR: In this paper , the authors reported a copper-catalyzed (5 + 3) annulation of donor-acceptor cyclopropanes with imidazolidines, thereby providing a straightforward method to access a library of saturated 1,4-diazocanes in moderate to excellent yields under mild reaction conditions.
Journal ArticleDOI
Diastereoselective Cyclopropanation through Michael Addition-Initiated Ring Closure between α,α-Dibromoketones and α,β-Unsaturated Fischer Carbene Complexes
Tomáš Tobrman,Martin Krupička,Peter Polák,Hana Dvořáková,Marek Čubiňák,Martin Babor,Dalimil Dvořák +6 more
Journal ArticleDOI
Synergistic Lewis-Brønsted Acid Catalysis in Cascade Cyclization of ortho-Alkynylaryl Cyclopropylketones for the Synthesis of 2,3-Dihydronaphtho[1,2-b]furans.
TL;DR: In this article , a synthesis method for the synthesis of 2,3-dihydronaphtho[1,2-b]furans employing synergistic Lewis-Brønsted acid catalyzed cyclization of ortho-alkynylarylcyclopropylketones has been developed.
References
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A new golden age for donor-acceptor cyclopropanes.
TL;DR: This Review highlights the appropriate tools for successfully employing donor-acceptor cyclopropanes in ring-opening reactions, cycloadditions, and rearrangements.
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