Journal ArticleDOI
Cationic salt-responsive bottle-brush polymers.
TLDR
A class of cationic bottle-brush polymers that show ionic strength-dependent stimuli responsiveness is prepared and becomes insoluble in solution due to the screening effect of salts that yield the once-dominant electrostatic interactions among QA species to hydrophobic-hydrophobic interactions.Abstract:
A class of cationic bottle-brush polymers that show ionic strength-dependent stimuli responsiveness is prepared. Brush polymers with norbornene as backbone and quaternary ammonium (QA)-containing polycaprolactone copolymers as side chains are synthesized by a combination of ring-opening metathesis polymerization, ring-opening polymerization, and click reaction. In water with low ionic strength, brush polymers are soluble due to the strong electrostatic repulsion between cationic QA groups. As the addition of salt to increase ionic strength, single brush polymers undergo a transition from extended conformation to collapsed state and finally become insoluble in solution due to the screening effect of salts that yield the once-dominant electrostatic interactions among QA species to hydrophobic-hydrophobic interactions.read more
Citations
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Quaternary ammonium-based biomedical materials: State-of-the-art, toxicological aspects and antimicrobial resistance.
TL;DR: Recent evidenced-based data on the biomedical applications of antimicrobial quaternary ammonium-containing biomaterials that are based on randomized human clinical trials, the golden standard in contemporary medicinal science, are included in the present review.
Journal ArticleDOI
Bottlebrush polymers: From controlled synthesis, self-assembly, properties to applications
Zili Li,Zili Li,Miao Tang,Shuang Liang,Mingyue Zhang,Gill M. Biesold,Yanjie He,Shu-Meng Hao,Woosung Choi,Yijiang Liu,Juan Peng,Zhiqun Lin +11 more
TL;DR: In this paper, the authors provide a comprehensive and critical summary that highlights the recent advances in BBPs in terms of their controlled syntheses, self-assembly, properties, and applications.
Journal ArticleDOI
Functionalized molecular bottlebrushes
TL;DR: A three-step synthetic strategy is established for the preparation of functionalized bottlebrush copolymers that could be functionalized with pyrene or biotin molecules through an esterification reaction and obtained in three linear synthetic steps starting from a commercially available monomer.
Journal ArticleDOI
Chitosan-based intelligent theragnosis nanocomposites enable pH-sensitive drug release with MR-guided imaging for cancer therapy
Eun Kyung Lim,Warayuth Sajomsang,Yuna Choi,Eunji Jang,Hwunjae Lee,Byunghoon Kang,Eunjung Kim,Seungjoo Haam,Jin Suck Suh,Sang J. Chung,Yong Min Huh +10 more
TL;DR: N Chitosan-DMNPs have potential as theragnosis nanocomposites for effective cancer therapy as well as diagnosing and monitoring therapeutic responses.
References
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Journal ArticleDOI
Emerging applications of stimuli-responsive polymer materials
Martien A. Cohen Stuart,Wilhelm T. S. Huck,Jan Genzer,Marcus Müller,Christopher K. Ober,Manfred Stamm,Gleb B. Sukhorukov,Igal Szleifer,Vladimir V. Tsukruk,Marek W. Urban,Françoise M. Winnik,Stefan Zauscher,Igor Luzinov,Sergiy Minko +13 more
TL;DR: This work reviews recent advances and challenges in the developments towards applications of stimuli-responsive polymeric materials that are self-assembled from nanostructured building blocks and provides a critical outline of emerging developments.
Journal ArticleDOI
Stimuli responsive polymers for biomedical applications
TL;DR: This critical review of polymers that can respond to external stimuli considers the types of stimulus response used in therapeutic applications and the main classes of responsive materials developed to date.
Journal ArticleDOI
Grafting: a versatile means to modify polymers Techniques, factors and applications
Amit Bhattacharya,B.N. Misra +1 more
TL;DR: Graft co-polymerization initiated by chemical treatment, photo-irradiation, high-energy radiation technique, etc. is documented in this article, where several prime controlling factors on grafting are discussed.
Journal ArticleDOI
Cylindrical molecular brushes: Synthesis, characterization, and properties
TL;DR: A detailed review of the physical properties of molecular brushers can be found in this article, with particular focus on synthesis via controlled radical polymerization techniques, where the authors present several strategies for their preparation.
Journal ArticleDOI
Stimuli-responsive molecular brushes
TL;DR: In this paper, the authors review the general aspects of molecular brushes and polymeric responsive systems and highlight the rational approaches to induce stimuli-responsiveness in molecular brush systems, which are unique for molecular brushes since these conformational changes can be restricted to a single molecule.