Journal ArticleDOI
Chitinases: in agriculture and human healthcare
TLDR
This review covers the recent advances of chitinases as a biocontrol agent and its various applications including preparation of medically important chitooligosaccharides, bioconversion of Chitin as well as in implementing chit inases as diagnostic and prognostic markers for numerous diseases and the prospect of their future utilization.Abstract:
Biological control of phytopathogenic fungi and insects continues to inspire the research and development of environmentally friendly bioactive alternatives. Potentially lytic enzymes, chitinases can act as a biocontrol agent against agriculturally important fungi and insects. The cell wall in fungi and protective covers, i.e. cuticle in insects shares a key structural polymer, chitin, a β-1,4-linked N-acetylglucosamine polymer. Therefore, it is advantageous to develop a common biocontrol agent against both of these groups. As chitin is absent in plants and mammals, targeting its metabolism will signify an eco-friendly strategy for the control of agriculturally important fungi and insects but is innocuous to mammals, plants, beneficial insects and other organisms. In addition, development of chitinase transgenic plant varieties probably holds the most promising method for augmenting agricultural crop protection and productivity, when properly integrated into traditional systems. Recently, human proteins with chitinase activity and chitinase-like proteins were identified and established as biomarkers for human diseases. This review covers the recent advances of chitinases as a biocontrol agent and its various applications including preparation of medically important chitooligosaccharides, bioconversion of chitin as well as in implementing chitinases as diagnostic and prognostic markers for numerous diseases and the prospect of their future utilization.read more
Citations
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Journal ArticleDOI
Biocontrol Yeasts: Mechanisms and Applications
TL;DR: Yeasts represent a largely unexplored field of research and plentiful opportunities for the development of commercial, yeast-based applications for plant protection exist, but the scarcity of fundamental studies on yeast biocontrol mechanisms and of registered yeast- based biocOntrol products is highlighted.
Journal ArticleDOI
Chitinases from Bacteria to Human: Properties, Applications, and Future Perspectives
Abhishek Rathore,Rinkoo D. Gupta +1 more
TL;DR: A review on properties and applications of chitinases starting from bacteria, followed by fungi, insects, plants, and vertebrates is presented in this paper, where a rational approach for improved catalytic activity for cost-effective field applications has also been explored.
Journal ArticleDOI
Antifungal Agents in Agriculture: Friends and Foes of Public Health
Verônica Soares Brauer,Caroline Patini Rezende,André Moreira Pessoni,Renato Graciano de Paula,Kanchugarakoppal S. Rangappa,Siddaiah Chandra Nayaka,Vijai Kumar Gupta,Fausto Almeida +7 more
TL;DR: In this article, the authors discuss the use of antifungal agents in agriculture worldwide, the need to develop new ant-agents, and improvement of regulations regarding ant-drug use.
Journal ArticleDOI
Chitinase-producing bacteria and their role in biocontrol
TL;DR: Chitinolytic microorganisms are likely to play an important role as biocontrol agents and pathogen antagonists and may also function in the control of postharvest rot.
Journal ArticleDOI
Chitinases—Potential Candidates for Enhanced Plant Resistance towards Fungal Pathogens
TL;DR: Chitinases in combination with recombinant technology can be a promising tool for improving plant resistance to fungal diseases.
References
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Journal ArticleDOI
Antifungal proteins from plants. Purification, molecular cloning, and antifungal properties of chitinases from maize seed.
Q.K. Huynh,Cathy M. Hironaka,Levine Elaine Beatrice,Christine E. Smith,Jeffry R. Borgmeyer,Dilip M. Shah +5 more
TL;DR: Comparison of the amino acid sequences of maize seed chitinases with those of previously published chit inases from monocot and dicot plants indicates that maize seed Chitinase A and B have diverged significantly from other chitInases.
Journal ArticleDOI
Identification of an antifungal chitinase from a potential biocontrol agent, Bacillus cereus 28-9.
TL;DR: An in vitro assay showed that the purified ChiCW had inhibitory activity on conidial germination of Botrytis elliptica, a major fungal pathogen of lily leaf blight.
Journal ArticleDOI
Family 19 chitinases of Streptomyces species: characterization and distribution.
Takeshi Watanabe,Ryo Kanai,Tomokazu Kawase,Toshiaki Tanabe,Masaru Mitsutomi,Shohei Sakuda,Kiyotaka Miyashita +6 more
TL;DR: Streptomyces family 19 chitinases are class IV type in terms of the presence and positions of deletions of amino acid sequences which are characteristic of plant class IV chit inases.
Journal ArticleDOI
High serum YKL-40 concentration is associated with cardiovascular and all-cause mortality in patients with stable coronary artery disease.
Jens Kastrup,Julia S. Johansen,Per Winkel,Jørgen Fischer Hansen,Per Hildebrandt,Gorm B. Jensen,Christian M. Jespersen,Erik Kjøller,Hans Jørn Kolmos,Inga Lind,Henrik Nielsen,Christian Gluud +11 more
TL;DR: High serum YKL-40 is associated with MI, cardiovascular and all-cause mortality in patients with stable CAD and following multivariable adjustment for cardiovascular risk factors and selected medical treatments Y contributed significantly to prediction of all- cause mortality.
Journal ArticleDOI
Comparative studies of chitinases A, B and C from Serratia marcescens
Svein Jarle Horn,Morten Sørlie,Gustav Vaaje-Kolstad,Anne Line Norberg,Bjørnar Synstad,Kjell Morten Vårum,V.G.H. Eijsink +6 more
TL;DR: The available data for Serratia chitinases show that the chitinolytic machinery of this bacterium consists of two processive exo-enzymes that degrade the chITin chains in opposite directions (ChiA and ChiB) and a non-processive endo-enzyme, ChiC.