Journal ArticleDOI
Chitinases: in agriculture and human healthcare
TLDR
This review covers the recent advances of chitinases as a biocontrol agent and its various applications including preparation of medically important chitooligosaccharides, bioconversion of Chitin as well as in implementing chit inases as diagnostic and prognostic markers for numerous diseases and the prospect of their future utilization.Abstract:
Biological control of phytopathogenic fungi and insects continues to inspire the research and development of environmentally friendly bioactive alternatives. Potentially lytic enzymes, chitinases can act as a biocontrol agent against agriculturally important fungi and insects. The cell wall in fungi and protective covers, i.e. cuticle in insects shares a key structural polymer, chitin, a β-1,4-linked N-acetylglucosamine polymer. Therefore, it is advantageous to develop a common biocontrol agent against both of these groups. As chitin is absent in plants and mammals, targeting its metabolism will signify an eco-friendly strategy for the control of agriculturally important fungi and insects but is innocuous to mammals, plants, beneficial insects and other organisms. In addition, development of chitinase transgenic plant varieties probably holds the most promising method for augmenting agricultural crop protection and productivity, when properly integrated into traditional systems. Recently, human proteins with chitinase activity and chitinase-like proteins were identified and established as biomarkers for human diseases. This review covers the recent advances of chitinases as a biocontrol agent and its various applications including preparation of medically important chitooligosaccharides, bioconversion of chitin as well as in implementing chitinases as diagnostic and prognostic markers for numerous diseases and the prospect of their future utilization.read more
Citations
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Journal ArticleDOI
Biocontrol Yeasts: Mechanisms and Applications
TL;DR: Yeasts represent a largely unexplored field of research and plentiful opportunities for the development of commercial, yeast-based applications for plant protection exist, but the scarcity of fundamental studies on yeast biocontrol mechanisms and of registered yeast- based biocOntrol products is highlighted.
Journal ArticleDOI
Chitinases from Bacteria to Human: Properties, Applications, and Future Perspectives
Abhishek Rathore,Rinkoo D. Gupta +1 more
TL;DR: A review on properties and applications of chitinases starting from bacteria, followed by fungi, insects, plants, and vertebrates is presented in this paper, where a rational approach for improved catalytic activity for cost-effective field applications has also been explored.
Journal ArticleDOI
Antifungal Agents in Agriculture: Friends and Foes of Public Health
Verônica Soares Brauer,Caroline Patini Rezende,André Moreira Pessoni,Renato Graciano de Paula,Kanchugarakoppal S. Rangappa,Siddaiah Chandra Nayaka,Vijai Kumar Gupta,Fausto Almeida +7 more
TL;DR: In this article, the authors discuss the use of antifungal agents in agriculture worldwide, the need to develop new ant-agents, and improvement of regulations regarding ant-drug use.
Journal ArticleDOI
Chitinase-producing bacteria and their role in biocontrol
TL;DR: Chitinolytic microorganisms are likely to play an important role as biocontrol agents and pathogen antagonists and may also function in the control of postharvest rot.
Journal ArticleDOI
Chitinases—Potential Candidates for Enhanced Plant Resistance towards Fungal Pathogens
TL;DR: Chitinases in combination with recombinant technology can be a promising tool for improving plant resistance to fungal diseases.
References
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Journal ArticleDOI
Efficiency of chitinolytic enzymes in the formation of Tricholoma matsutake protoplasts
Daizo Koga,Nobuyuki Sueshige,Kazuhiko Orikono,Toshihiko Utsumi,Shuhei Tanaka,Yoshio Yamada,Akio Ide +6 more
Journal Article
Purification and Characterization of Acidic Chitinases from Gizzards of Broiler ( Gallus gallus L. )
TL;DR: Acidic chitinases from the gizzards of a broiler were purified to homogeneity, using precipitation with , ion exchanger chromatography, gel filtration, chromatofocusing and hydrophobic interaction chromatography; little homology was found with either microbial and plant chit inases, or egg white lysozyme.
Journal ArticleDOI
Purification and Characterization of Extracellular Chitinase from a Novel Strain Aspergillus fumigatus CS-01
TL;DR: Analysis of the morphological feature and the ITS rDNA sequence reveals that strain CS-01 belongs to Aspergillus fumigatus, and purification of the chitinase indicates that it is a monomer with the relative molecular mass estimated to be 4.50×104.
Journal ArticleDOI
Production and Biochemical Characterization of Insecticidal Enzymes from Aspergillus fumigatus Toward Callosobruchus maculatus
TL;DR: Aspergillus fumigatus is described as a higher producer of hydrolytic enzymes secreted in response to the presence of the Callosobruchus maculatus bruchid pest, which was able to grow over cowpea weevil shells as a unique carbon source.
Journal ArticleDOI
Effect of mycolase and amphotericin B on Candida albicans and Candida pseudotropicalis in vitro and in vivo
TL;DR: Mycolase alone or in combination with amphotericin B did not appreciably enhance phagocytosis or intracellular killing of the yeasts by unstimulated mouse peritoneal macrophages and studies on mice infected systemically with C. albicans showed that mycolase only slightly enhanced amphoteric in B therapy.