Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
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TLDR
Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.About:
This article is published in The Lancet.The article was published on 2020-03-28 and is currently open access. It has received 20189 citations till now. The article focuses on the topics: Cohort study & Retrospective cohort study.read more
Citations
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COVID-19 pandemic-a focused review for clinicians.
TL;DR: The virological characteristics of SARS-CoV-2 and clinical course of COVID-19 are described with an emphasis on diagnostic challenges, duration of viral shedding, severity markers and current treatment options.
Journal ArticleDOI
Medically Necessary, Time-Sensitive Procedures: Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic.
Vivek N. Prachand,Ross Milner,Peter Angelos,Mitchell C. Posner,John J. Fung,Nishant Agrawal,Valluvan Jeevanandam,Jeffrey B. Matthews +7 more
TL;DR: A scoring system is described that systematically integrates factors to facilitate decision-making and triage for MeNTS procedures, and appropriately weighs individual patient risks with the ethical necessity of optimizing public health concerns.
Journal ArticleDOI
Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis.
Adam L. Booth,Angus B. Reed,Sonia Ponzo,Arrash Yassaee,Mert Aral,David Plans,Alain B. Labrique,Diwakar Mohan +7 more
TL;DR: In this paper, a systematic review was conducted using standardized methodology, searching two electronic databases (PubMed and SCOPUS) for relevant literature published between 1st January 2020 and 9th July 2020.
Journal ArticleDOI
Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank.
Claire L. Niedzwiedz,Catherine A. O'Donnell,Bhautesh Dinesh Jani,Evangelia Demou,Frederick K. Ho,Carlos Celis-Morales,Barbara I. Nicholl,Frances S. Mair,Paul Welsh,Naveed Sattar,Jill P. Pell,Srinivasa Vittal Katikireddi +11 more
TL;DR: Some minority ethnic groups have a higher risk of confirmed SARS-CoV-2 infection in the UK Biobank study, which was not accounted for by differences in socioeconomic conditions, baseline self-reported health or behavioural risk factors.
Journal ArticleDOI
Characterization of Myocardial Injury in Patients With COVID-19.
Gennaro Giustino,Lori B. Croft,Giulio G. Stefanini,Renato Bragato,Jeffrey J. Silbiger,Marco Vicenzi,Tatyana Danilov,Nina Kukar,Nada Shaban,Annapoorna Kini,Anton Camaj,Solomon Bienstock,Eman Rashed,Karishma Rahman,Connor P. Oates,Samantha Buckley,Lindsay Elbaum,Derya Arkonac,Ryan Fiter,Ranbir Singh,Emily Li,Victor Razuk,Sam E. Robinson,Michael L. Miller,Benjamin Bier,Valeria Donghi,Marco Pisaniello,Riccardo Mantovani,Giuseppe Pinto,Irene Rota,Sara Baggio,Mauro Chiarito,Fabio Fazzari,Ignazio Cusmano,Mirko Curzi,Richard Ro,Waqas Malick,Mazullah Kamran,Roopa Kohli-Seth,Adel Bassily-Marcus,Eric Neibart,Gregory Serrao,Gila Perk,Donna M. Mancini,Vivek Y. Reddy,Sean Pinney,George Dangas,Francesco Blasi,Samin K. Sharma,Roxana Mehran,Gianluigi Condorelli,Gregg W. Stone,Valentin Fuster,Stamatios Lerakis,Martin E. Goldman +54 more
TL;DR: An international, multicenter cohort study including 7 hospitals in New York City and Milan of hospitalized patients with laboratory-confirmed COVID-19 who had undergone transthoracic echocardiographic (TTE) and electrocardiographic evaluation during their index hospitalization found cardiac structural abnormalities were present in nearly two-thirds of patients with myocardial injury.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Mervyn Singer,Clifford S. Deutschman,Christopher W. Seymour,Manu Shankar-Hari,Djillali Annane,Michael Bauer,Rinaldo Bellomo,Gordon R. Bernard,Jean-Daniel Chiche,Craig M. Coopersmith,Richard S. Hotchkiss,Mitchell M. Levy,John C. Marshall,Greg S. Martin,Steven M. Opal,Gordon D. Rubenfeld,Gordon D. Rubenfeld,Tom van der Poll,Jean Louis Vincent,Derek C. Angus +19 more
TL;DR: The task force concluded the term severe sepsis was redundant and updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsi or at risk of developing sepsic shock.
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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.
Qun Li,Xuhua Guan,Peng Wu,Xiaoye Wang,Lei Zhou,Yeqing Tong,Ruiqi Ren,Kathy Leung,Eric H. Y. Lau,Jessica Y. Wong,Xuesen Xing,Nijuan Xiang,Yang Wu,Chao Li,Chen Qi,Dan Li,Tian Liu,Jing Zhao,Man Liu,Wenxiao Tu,Chuding Chen,Lianmei Jin,Rui Yang,Qi Wang,Suhua Zhou,Rui Wang,Hui Liu,Yingbo Luo,Yuan Liu,Ge Shao,Huan Li,Zhongfa Tao,Yang Yang,Yang Yang,Zhiqiang Deng,Boxi Liu,Zhitao Ma,Yanping Zhang,Guoqing Shi,Tommy Tsan-Yuk Lam,Joseph T. Wu,George F. Gao,George F. Gao,Benjamin J. Cowling,Bo Yang,Gabriel M. Leung,Zijian Feng +46 more
TL;DR: There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
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