Journal ArticleDOI
Community-acquired pneumonia
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This article is published in The Lancet.The article was published on 1998-12-19. It has received 1403 citations till now. The article focuses on the topics: Community-acquired pneumonia.read more
Citations
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DNA-release by Streptococcus pneumoniae autolysin LytA induced Krueppel-like factor 4 expression in macrophages.
Toni Herta,Aritra Bhattacharyya,Christian Bollensdorf,Christin Kabus,Pedro García,Norbert Suttorp,Stefan Hippenstiel,Janine Zahlten +7 more
TL;DR: It is shown that pneumococci-related KLF4 induction in macrophages is mediated via a PAMP-DAMP induction mechanism involving a hitherto unknown host cell DNA sensor leading to a more proinflammatory macrophage phenotype.
Journal ArticleDOI
Mycoplasma pneumoniae: Usual suspect and unsecured Diagnosis in the acute setting
TL;DR: A typical case of pneumonia due to Mycoplasma pneumoniae in a young adult with mild pharyngitis as the leading symptom is described to provide a review on the clinical aspects of the disease that are important in the ED setting.
Journal ArticleDOI
Preventing Mismanagement of Community-Acquired Pneumonia at an Urban Public Hospital: Implications for Institution-Specific Practice Guidelines
David N. Schwartz,Alice Furumoto-Dawson,Gail S. Itokazu,Mustafa Chinikamwala,Steven Levasseur,Robert A. Weinstein +5 more
TL;DR: A chart-based retrospective study was conducted to assess institutional performance of key diagnostic and therapeutic interventions and to identify areas amenable to improvement in the management of community-acquired pneumonia (CAP) as discussed by the authors.
Journal ArticleDOI
Resistance Phenotypes and Genotypes of Erythromycin-Resistant Streptococcus pneumoniae Isolates in Beijing and Shenyang, China
TL;DR: Of a total of 192 Streptococcus pneumoniae isolates, 149 (77.6%) were not susceptible to erythromycin and 117 (79.1%) contained the erm(B) gene, and 16 (10.8%) harbored the mef(A) gene.
Journal ArticleDOI
Respiratory muscles dysfunction and respiratory diseases
TL;DR: It was proved that the role of RM in the development of respiratory failure depends on the form and stage of the pulmonary pathology and the severity of systemic manifestations of these diseases: excessive proteolysis, oxidative stress, hypoxia, chronic systemic inflammation.
References
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Mortality, morbidity, and psychosocial outcomes of persons spinal cord injured more than 20 years ago.
Gale G. Whiteneck,Susan Charlifue,Hans L. Frankel,M H Fraser,B P Gardner,Kenneth A. Gerhart,K R Krishnan,Robert R. Menter,I Nuseibeh,D J Short,John Russell Silver +10 more
TL;DR: Declines with age were found in measures of handicap and life satisfaction, but three quarters of those interviewed reported generally good health and rated their current quality of life as either good or excellent.
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Causes of death during the first 12 years after spinal cord injury
TL;DR: Though some cause-specific mortality rates for spinal cord injured persons have declined dramatically, many remain substantially above normal and improved methods for preventing and managing these fatal complications must be developed.
Journal Article
Risk factors for Clostridium difficile carriage and C. difficile-associated diarrhea in a cohort of hospitalized patients
TL;DR: C. difficile was a common Nosocomial infection on this ward, resulting in asymptomatic carriage more often than diarrhea and accounting for one-fifth of all cases of nosocomial diarrhea.
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Risk Factors for Clostridium difficile Carriage and C. difficile-Associated Diarrhea in a Cohort of Hospitalized Patients
TL;DR: In this paper, a prospective cohort study of 399 consecutive patients in a single ward over an 11-month period was conducted to identify risk factors for nosocomial C. difficile colonization and diarrhea.
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Successful control of Clostridium difficile infection in an elderly care unit through use of a restrictive antibiotic policy.
Cliodna A. M. McNulty,Margaret Logan,Ian P. Donald,Debbie Ennis,Denise Taylor,R. N. Baldwin,Mira Bannerjee,Keith A. V. Cartwright +7 more
TL;DR: The use of narrow-spectrum antibiotics for hospital treatment of community-acquired infections in the elderly should be encouraged.