Journal ArticleDOI
Community-acquired pneumonia
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This article is published in The Lancet.The article was published on 1998-12-19. It has received 1403 citations till now. The article focuses on the topics: Community-acquired pneumonia.read more
Citations
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Journal ArticleDOI
Early identification of severe community-acquired pneumonia: a retrospective observational study.
Frances Grudzinska,Kerrie Aldridge,Sian Hughes,Peter Nightingale,Dhruv Parekh,Mansoor N Bangash,Rachel Dancer,Jaimin Patel,Elizabeth Sapey,David R Thickett,Davinder Dosanjh +10 more
TL;DR: All four scoring systems can stratify according to increasing risk in CAP; however, when a confident diagnosis of pneumonia can be made, these data support the use of pneumonia-specific tools rather than generic sepsis or early warning scores.
Journal ArticleDOI
Use of molecular assays for the diagnosis of influenza.
TL;DR: Examples of real-time assays for the detection of influenza viruses, including the highly pathogenic influenza A strains H5N1 and H7N7, will be discussed and promising new techniques that allow detailed genotyping of viruses or multiplex detection of several respiratory pathogens from a unique specimen will also be discussed.
Book ChapterDOI
Chapter 22 – Environmentally Transmitted Pathogens
TL;DR: This chapter describes a variety of pathogens found in the environment that are capable of infecting humans and causing disease, including bacteria, parasites and viruses.
Journal ArticleDOI
Estradiol resolves pneumonia via ERβ in regulatory T cells
Ye Xiong,Qiong Zhong,Tsvi Palmer,Alison Benner,Lan Wang,Karthik Suresh,Rachel L. Damico,Franco R. D'Alessio +7 more
TL;DR: The therapeutic role for E2 is supported in promoting resolution of lung inflammation after PNA via ERβ Tregs, and the in vivo therapeutic effects of E2 were lost in Treg-depleted mice (Foxp3DTR mice).
Journal ArticleDOI
Rapid detection of respiratory organisms with FilmArray respiratory panel and its impact on clinical decisions in Shanghai, China, 2016-2018
Yi-Yi Qian,Jing-Wen Ai,Jing Wu,Shenglei Yu,Peng Cui,Yan Gao,Jialin Jin,Xinhua Weng,Wenhong Zhang +8 more
TL;DR: The diagnostic potential and clinical impact of an automated multiplex PCR platform, specially designed for pathogen detection in respiratory tract infections in adults with unexplained pneumonia, are evaluated.
References
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Journal ArticleDOI
Mortality, morbidity, and psychosocial outcomes of persons spinal cord injured more than 20 years ago.
Gale G. Whiteneck,Susan Charlifue,Hans L. Frankel,M H Fraser,B P Gardner,Kenneth A. Gerhart,K R Krishnan,Robert R. Menter,I Nuseibeh,D J Short,John Russell Silver +10 more
TL;DR: Declines with age were found in measures of handicap and life satisfaction, but three quarters of those interviewed reported generally good health and rated their current quality of life as either good or excellent.
Journal ArticleDOI
Causes of death during the first 12 years after spinal cord injury
TL;DR: Though some cause-specific mortality rates for spinal cord injured persons have declined dramatically, many remain substantially above normal and improved methods for preventing and managing these fatal complications must be developed.
Journal Article
Risk factors for Clostridium difficile carriage and C. difficile-associated diarrhea in a cohort of hospitalized patients
TL;DR: C. difficile was a common Nosocomial infection on this ward, resulting in asymptomatic carriage more often than diarrhea and accounting for one-fifth of all cases of nosocomial diarrhea.
Journal ArticleDOI
Risk Factors for Clostridium difficile Carriage and C. difficile-Associated Diarrhea in a Cohort of Hospitalized Patients
TL;DR: In this paper, a prospective cohort study of 399 consecutive patients in a single ward over an 11-month period was conducted to identify risk factors for nosocomial C. difficile colonization and diarrhea.
Journal ArticleDOI
Successful control of Clostridium difficile infection in an elderly care unit through use of a restrictive antibiotic policy.
Cliodna A. M. McNulty,Margaret Logan,Ian P. Donald,Debbie Ennis,Denise Taylor,R. N. Baldwin,Mira Bannerjee,Keith A. V. Cartwright +7 more
TL;DR: The use of narrow-spectrum antibiotics for hospital treatment of community-acquired infections in the elderly should be encouraged.