Journal ArticleDOI
Community-acquired pneumonia
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This article is published in The Lancet.The article was published on 1998-12-19. It has received 1403 citations till now. The article focuses on the topics: Community-acquired pneumonia.read more
Citations
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Toll/IL-1R Domain-Containing Adaptor Protein (TIRAP) Is a Critical Mediator of Antibacterial Defense in the Lung against Klebsiella pneumoniae but Not Pseudomonas aeruginosa
Samithamby Jeyaseelan,Scott K. Young,Masahiro Yamamoto,Patrick G. Arndt,Shizuo Akira,Jay K. Kolls,G. Scott Worthen +6 more
TL;DR: It is suggested that TLR5 plays an essential role for Pa-induced neutrophil influx via LIX production, yet it is necessary for MIP-2, TNF-α, and IL-6 production, but not Lix production.
Journal ArticleDOI
Incidence, risk factors, and mortality from pneumonia developing late after hematopoietic stem cell transplantation.
Chien-Shing Chen,Michael Boeckh,Kristy Seidel,Joan G. Clark,Emin Kansu,David K. Madtes,John L. Wagner,John L. Wagner,Robert P. Witherspoon,Claudio Anasetti,F R Appelbaum,William I. Bensinger,Deeg Hj,Paul J. Martin,Jean E. Sanders,R Storb,Jan Storek,James C. Wade,James C. Wade,M. Siadak,Mary E.D. Flowers,Keith M. Sullivan +21 more
TL;DR: The data suggest that extension of PCP prophylaxis may be beneficial in high-risk autograft recipients and further study of long-term anti-infective proPHylaxis based on patient risk factors after SCT appear warranted.
Journal ArticleDOI
Antibiotic use, hospital admissions, and mortality before and after implementing guidelines for nursing home-acquired pneumonia.
TL;DR: The increase in the use of PA provides evidence that care within SNFs can be significantly changed using standard quality improvement techniques, and use of the guidelines did not significantly affect mortality.
Journal ArticleDOI
Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients.
Marta Di Pasquale,Giovanni Sotgiu,Andrea Gramegna,Dejan Radovanovic,Silvia Terraneo,Luis F. Reyes,Jan Rupp,Juan González del Castillo,Francesco Blasi,Stefano Aliberti,Marcos I. Restrepo,Glimp Investigators +11 more
TL;DR: Of patients with pneumonia coming from the community, 18% are immunocompromised, which has to be taken into consideration when choosing empirical therapy.
Journal ArticleDOI
Role of the Microbiology Laboratory in the Diagnosis of Lower Respiratory Tract Infections
Larry G. Reimer,Karen C. Carroll +1 more
TL;DR: The role of the clinical microbiology laboratory in the etiologic diagnosis of nosocomial and complicated pneumonias is more extensive and, in addition to evaluation of respiratory secretions, may include cultures of blood, pleural fluid, and specimens obtained by bronchoscopy.
References
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Mortality, morbidity, and psychosocial outcomes of persons spinal cord injured more than 20 years ago.
Gale G. Whiteneck,Susan Charlifue,Hans L. Frankel,M H Fraser,B P Gardner,Kenneth A. Gerhart,K R Krishnan,Robert R. Menter,I Nuseibeh,D J Short,John Russell Silver +10 more
TL;DR: Declines with age were found in measures of handicap and life satisfaction, but three quarters of those interviewed reported generally good health and rated their current quality of life as either good or excellent.
Journal ArticleDOI
Causes of death during the first 12 years after spinal cord injury
TL;DR: Though some cause-specific mortality rates for spinal cord injured persons have declined dramatically, many remain substantially above normal and improved methods for preventing and managing these fatal complications must be developed.
Journal Article
Risk factors for Clostridium difficile carriage and C. difficile-associated diarrhea in a cohort of hospitalized patients
TL;DR: C. difficile was a common Nosocomial infection on this ward, resulting in asymptomatic carriage more often than diarrhea and accounting for one-fifth of all cases of nosocomial diarrhea.
Journal ArticleDOI
Risk Factors for Clostridium difficile Carriage and C. difficile-Associated Diarrhea in a Cohort of Hospitalized Patients
TL;DR: In this paper, a prospective cohort study of 399 consecutive patients in a single ward over an 11-month period was conducted to identify risk factors for nosocomial C. difficile colonization and diarrhea.
Journal ArticleDOI
Successful control of Clostridium difficile infection in an elderly care unit through use of a restrictive antibiotic policy.
Cliodna A. M. McNulty,Margaret Logan,Ian P. Donald,Debbie Ennis,Denise Taylor,R. N. Baldwin,Mira Bannerjee,Keith A. V. Cartwright +7 more
TL;DR: The use of narrow-spectrum antibiotics for hospital treatment of community-acquired infections in the elderly should be encouraged.