Journal ArticleDOI
Community-acquired pneumonia
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This article is published in The Lancet.The article was published on 1998-12-19. It has received 1403 citations till now. The article focuses on the topics: Community-acquired pneumonia.read more
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2018 recommendations for the management of community acquired pneumonia
Ricardo de Amorim Corrêa,André Nathan Costa,Fernando Luiz Cavalcanti Lundgren,Lessandra Michelin,Mara Rúbia Fernandes de Figueiredo,Marcelo Alcântara Holanda,Mauro Gomes,Paulo José Zimermann Teixeira,Ricardo Martins,Rodney Luiz Frare e Silva,Rodrigo Abensur Athanazio,Rosemeri Maurici da Silva,Mônica Corso Pereira +12 more
TL;DR: Thirteen members with recognized experience in CAP in Brazil who identified issues relevant to clinical practice that require updates given the publication of new epidemiological and scientific evidence are summoned.
Journal ArticleDOI
Incidence and etiology of community-acquired pneumonia in the elderly in a prospective population-based study.
Arto A. Palmu,Annika Saukkoriipi,Marja Snellman,Jukka Jokinen,Päivi Torkko,Thedi Ziegler,Tarja Kaijalainen,William P. Hausdorff,Vincent Verlant,Terhi Kilpi +9 more
TL;DR: A feasible methodology for capturing endpoints in a vaccine trial for the prevention of pneumonia in the elderly population is developed and documented.
Journal ArticleDOI
The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design.
TL;DR: The structure of AlrSP is solved, an essential step towards the development of an accurate pharmacophore model of the enzyme, and an important contribution towards the on-going alanine racemase structure-based drug design project.
Journal ArticleDOI
Prediction of the Pathogens That Are the Cause of Pneumonia by the Battlefield Hypothesis
Takashi Hirama,Takefumi Yamaguchi,Hitoshi Miyazawa,Tomoaki Tanaka,Giichi Hashikita,Etsuko Kishi,Yoshimi Tachi,Shun Takahashi,Keiji Kodama,Hiroshi Egashira,Akemi Yokote,Kunihiko Kobayashi,Makoto Nagata,Toshiaki Ishii,Manabu Nemoto,Masahiko Tanaka,Koichi Fukunaga,Satoshi Morita,Minoru Kanazawa,Koichi Hagiwara +19 more
TL;DR: The battlefield hypothesis enabled legitimate interpretation of the PCR results and predicted pneumonia in which the pathogenic role of the organism was suggested by the clinical test, and may help to promote targeted therapies for pneumonia.
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Piperacillin/tazobactam in the treatment of polymicrobial infections.
TL;DR: P Piperacillin/tazobactam, a new combination broad-spectrum antibiotic and potent β-lactamase inhibitor, can be used for the treatment of infections caused by piperacillin-sensitive microorganisms as well as β- lactamases-producing, piperACillin-resistant organisms.
References
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Mortality, morbidity, and psychosocial outcomes of persons spinal cord injured more than 20 years ago.
Gale G. Whiteneck,Susan Charlifue,Hans L. Frankel,M H Fraser,B P Gardner,Kenneth A. Gerhart,K R Krishnan,Robert R. Menter,I Nuseibeh,D J Short,John Russell Silver +10 more
TL;DR: Declines with age were found in measures of handicap and life satisfaction, but three quarters of those interviewed reported generally good health and rated their current quality of life as either good or excellent.
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Causes of death during the first 12 years after spinal cord injury
TL;DR: Though some cause-specific mortality rates for spinal cord injured persons have declined dramatically, many remain substantially above normal and improved methods for preventing and managing these fatal complications must be developed.
Journal Article
Risk factors for Clostridium difficile carriage and C. difficile-associated diarrhea in a cohort of hospitalized patients
TL;DR: C. difficile was a common Nosocomial infection on this ward, resulting in asymptomatic carriage more often than diarrhea and accounting for one-fifth of all cases of nosocomial diarrhea.
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Risk Factors for Clostridium difficile Carriage and C. difficile-Associated Diarrhea in a Cohort of Hospitalized Patients
TL;DR: In this paper, a prospective cohort study of 399 consecutive patients in a single ward over an 11-month period was conducted to identify risk factors for nosocomial C. difficile colonization and diarrhea.
Journal ArticleDOI
Successful control of Clostridium difficile infection in an elderly care unit through use of a restrictive antibiotic policy.
Cliodna A. M. McNulty,Margaret Logan,Ian P. Donald,Debbie Ennis,Denise Taylor,R. N. Baldwin,Mira Bannerjee,Keith A. V. Cartwright +7 more
TL;DR: The use of narrow-spectrum antibiotics for hospital treatment of community-acquired infections in the elderly should be encouraged.