Journal ArticleDOI
Conjugates of stimuli-responsive polymers and proteins
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This chapter focuses on the synthesis and applications of covalent conjugates of proteins and stimuli-responsive or “smart” polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2007-08-01. It has received 303 citations till now. The article focuses on the topics: Smart polymer & Streptavidin.read more
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New directions in thermoresponsive polymers.
TL;DR: By highlighting recent examples of newly developed thermoresponsive polymer systems, it is hoped to promote the development of new generations of smart materials.
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PEG hydrogels for the controlled release of biomolecules in regenerative medicine.
TL;DR: The design criteria that are important in maintaining the availability and stability of the biomolecules as well as the mechanisms for loading of biomolecule within PEG hydrogels will also be discussed.
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Poly(N-isopropylacrylamide) Phase Diagrams: Fifty Years of Research.
Avraham Halperin,Avraham Halperin,Martin Kröger,Françoise M. Winnik,Françoise M. Winnik,Françoise M. Winnik +5 more
TL;DR: The reported phase diagrams of poly(N-isopropylacrylamide) (PNIPAM) are surveyed, the differences and comment on theoretical ideas regarding their possible origins are discussed, and open questions in this reputably mature domain are alerted.
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Stimuli-responsive polymers: Biomedical applications and challenges for clinical translation ☆
TL;DR: This article briefly overviews the field of stimuli-responsive polymers and describes some of the most successful biomedical applications to date of such "smart" polymers.
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Stimuli-Responsive Polymeric Systems for Biomedical Applications
TL;DR: The general aspects of the different types of stimuli that can be used to modulate the response are reviewed mainly for the case of hydrogels and surfaces, based on natural‐origin or biodegradable macromolecules.
References
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Journal ArticleDOI
Click Chemistry: Diverse Chemical Function from a Few Good Reactions.
TL;DR: In this paper, a set of powerful, highly reliable, and selective reactions for the rapid synthesis of useful new compounds and combinatorial libraries through heteroatom links (C-X-C), an approach called click chemistry is defined, enabled, and constrained by a handful of nearly perfect "springloaded" reactions.
Book
Methods of Biochemical Analysis
TL;DR: The Radiation Inactivation Method as a Tool to Study Structure-Function Relationships in Proteins Immunoassay with Electrochemical Detection and Theory and Newer Technology Assays for Superoxide Dismutase are studied.
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Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase.
TL;DR: Methoxypolyethylene glycols and catalase modified by covalent attachment of PEG-1900 to 43% of the amino groups exhibited enhanced circulating lives in the blood of acatalasemic mice during repetitive intravenous injections and no evidence of tissue or organ damage was seen.
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Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostics
TL;DR: Polymers and hydrogels have been synthesized which phase separate from aqueous solutions when the temperature is raised through a critical temperature region (LCST).