Open Access
Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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Biological Roles of Olfactory Ensheathing Cells in Facilitating Neural Regeneration: A Systematic Review
TL;DR: A systematic review regarding OECs’ beneficial roles in neural regeneration, and the unique properties of these cells that may exert a potential advantage over other cellular transplants are provided.
Journal ArticleDOI
Observations on cerebellar granule cells in tissue culture. A silver and electron microscopic study.
TL;DR: In long-term organized cultures of newborn mouse cerebellum, granule cell neurons were studied with silver impregnation and electron microscopy as mentioned in this paper, and the results showed that granule cells were more sensitive to the presence of silver than other neurons.
Journal ArticleDOI
Degenerative phenomena and reactive modifications of the adult rat inferior olivary neurons following axotomy and disconnection from their targets.
TL;DR: The results show that although adult axotomized inferior olivary neurons undergo severe regressive modifications leading to a conspicuous cell loss, at least a subset of them is resistant to the lesion, and the long-lasting expression of several axon-growth associated markers expressed in these neurons in response to injury reveals that they are endowed with a strong intrinsic regenerative potential.
Journal ArticleDOI
Grafts of syngenic cultured, adult dorsal root ganglion-derived Schwann cells to the injured spinal cord of adult rats: preliminary morphological studies.
TL;DR: Highly enriched cultures of Schwann cells were obtained from adult rat dorsal root ganglia and implanted in the spinal cord of syngenic adult rats at the site of an acute compression lesion, reducing central cavitation and astrocytic gliosis.
Journal ArticleDOI
Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration
TL;DR: Two priming lesions are shown to promote dramatic regeneration, within and beyond the lesion, and it is hypothesized that the first lesion enhances intrinsic growth capacity, and the second one sustains it, providing a paradigm for promoting CNS regeneration after injury.
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