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Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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THE FINE STRUCTURE OF THE LATERAL VESTIBULAR NUCLEUS IN THE RAT I. Neurons and Neuroglial Cells
TL;DR: The lateral vestibular nucleus consists of multipolar isodendritic neurons of various sizes The distal segments of some dendrites display broad expansions packed with slender mitochondria and glycogen particles, and the suggestion is advanced that they are manifestations of architectonic plasticity in the mature central nervous system.
Journal ArticleDOI
Lysosomes and gerl in normal and chromatolytic neurons of the rat ganglion nodosum
TL;DR: Electron microscopic images suggest that its smooth endoplasmic reticulum produces a variety of lysosomes in several ways: coated vesicles that separate from the Reticulum; dense bodies that arise from focal areas dilated with granular or membranous material; and the number of autophagic vacuoles increases following operation.
Journal ArticleDOI
Lysosomes in the rat sciatic nerve following crush
Eric Holtzman,Alex B. Novikoff +1 more
TL;DR: Peripheral nerves undergoing degeneration are favorable material for studying the types, origins, and functions of lysosomes, and the breakdown of organelles within these vacuoles may have significance for the reorganization of the axoplasm preparatory to regeneration.
Journal ArticleDOI
Effects of short- and long-term Schwann cell denervation on peripheral nerve regeneration, myelination, and size.
TL;DR: It is found that short‐term denervation of ≤4weeks did not affect axonal regeneration but more prolonged denervation profoundly reduced the numbers of backlabeled motor neurons and axons in the distal nerve stump, yet atrophic Schwann cells retained their capacity to remyelinate regenerated axons.
Journal ArticleDOI
Age, experience and the changing brain
TL;DR: The effects of age, experience, sex, and injury on the cortex are described and some general conclusions are attempted to reach.
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