Open Access
Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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Connectivity of neural transplants in adult rats: Analysis of afferents and efferents of neocortical transplants in the cerebellar hemisphere
Monica M. Oblinger,Gopal D. Das +1 more
TL;DR: Embryonic neocortical tissue, obtained from 17-day-old Long-Evans rat embryos, was transplanted into the intact cerebellar hemisphere of normal adult rat hosts, and all transplants had developed massive intratransplant connections.
Journal ArticleDOI
Anatomical and physiological properties of the projection from the sensory cortex to the motor cortex in normal cats: the difference between corticocortical and thalamocortical projections
TL;DR: This study provided a basis for examining the modifiability of association fibers after elimination of VL input to the motor cortex and concluded that association fibers effective for producing EPSPs terminate primarily on non-pyramidal cells in layer II and III whereas VL fibers terminate not only on pyramidal but also on non -pyramides cells in layers III and V.
Journal ArticleDOI
Delayed death of identified reticulospinal neurons after spinal cord injury in lampreys.
TL;DR: The data show that SCI induces delayed cell death in lamprey spinal‐projecting neurons and suggest that the reason why some neurons are “bad regenerators” is that they are already undergoing apoptotic cell death, and protection from apoptosis may be necessary in order to enhance axonal regeneration after SCI.
Journal ArticleDOI
Time Course Analysis of Gene Expression Patterns in Zebrafish Eye During Optic Nerve Regeneration.
Amy McCurley,Gloria V. Callard +1 more
TL;DR: Time course analysis of global gene expression patterns in the zebrafish eye after ONX can help to elucidate cellular and molecular mechanisms that contribute to a successful neuroregeneration, and provide an entry point for functional analyses.
Journal ArticleDOI
Axonal guidance channels in peripheral nerve regeneration
TL;DR: This review discusses several strategies that have been employed to enhance the regenerative effectiveness of artificial nerve guidance channels, including the use of scaffolds, the integration of contact-mediated cues within the tubular construct, and incorporation or delivery of exogenous growth factors into the conduit lumen uniformly or in a gradient form.
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