Open Access
Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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Journal ArticleDOI
Sciatic nerve injury: a simple and subtle model for investigating many aspects of nervous system damage and recovery.
Luis E. Savastano,Sergio Laurito,Marcos René Fitt,Jorge A. Rasmussen,Virginia Gonzalez Polo,Sean I. Patterson +5 more
TL;DR: A historical review of the contributions of sciatic nerve injury to the current understanding of fundamental questions in the neurosciences, and an assessment of its continuing capacity to address these and future problems are provided.
Journal ArticleDOI
Neurotrophins reduce degeneration of injured ascending sensory and corticospinal motor axons in adult rat spinal cord.
TL;DR: In this paper, a transection of the dorsal column sensory and corticospinal motor tracts at T9 and anterograde tracing of the axons from the sciatic nerve and motor cortex, respectively.
Journal ArticleDOI
Electron microscopic studies of the development of new neurohaemal contacts in the median eminence of the rat after hypophysectomy.
TL;DR: It is suggested that the greater degree of cell loss from the supraoptic as opposed to the paraventricular nuclei puts the parventricular axons at an advantage in competing for space on the basement membrane around the perivascular space of the newly formed capillaries.
Journal ArticleDOI
Astrocytes from adult rat optic nerves are nonpermissive for regenerating retinal ganglion cell axons
TL;DR: The failure of mammalian RGC axons to regrow within the lesioned optic nerve environment is, at least in part, due to nonpermissive aspects of adult "reactive" optic nerve astrocytes, but the cell intrinsic growth potential of RGCs appears to influence their ability to extend axons on cellular substrates.
Journal ArticleDOI
Dendritic structural plasticity.
TL;DR: This paper reviewed classical and recent evidence of dendrite plasticity in invertebrates and vertebrates and current progress in the understanding of the molecular mechanisms that underlie this plasticity.
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