Open Access
Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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Journal ArticleDOI
Cell Therapy for Spinal Cord Injury by Neural Stem/Progenitor Cells Derived from iPS/ES Cells
Osahiko Tsuji,Kyoko Miura,Kanehiro Fujiyoshi,Suketaka Momoshima,Masaya Nakamura,Hideyuki Okano +5 more
TL;DR: The neural induction of mouse embryonic stem cells and induced pluripotent stem cells are outlined, their therapeutic efficacy in spinal cord injury, and their safety in vivo.
Journal ArticleDOI
Axonal sprouts containing calcitonin gene-related peptide and substance P form pericellular baskets around large diameter neurons after sciatic nerve transection in the rat
Elspeth M. McLachlan,P. Hu +1 more
TL;DR: It is found that axons of small sensory neurons immunoreactive for these peptides also form rings around large diameter dorsal root ganglion cells of adult rats after sciatic nerve transection, concurrently with the development of rings of noradrenergic terminals.
Journal ArticleDOI
Sensory axon regeneration: rebuilding functional connections in the spinal cord.
TL;DR: This review focuses on recent advances in sensory axon regeneration, including studies assessing the ability of sensory axons to reconnect with their original synaptic targets.
Journal ArticleDOI
Adaptive changes in the injured spinal cord and their role in promoting functional recovery
Karim Fouad,Arthur D.Y. Tse +1 more
TL;DR: Plasticity throughout the entire central nervous system induced by spinal cord injuries (SCIs) with an emphasis on sprouting of descending spinal tracts is discussed, because this sprouting occurs spontaneously, it not only lends itself as a recovery mechanism, but also opens potential treatment avenues to promote further functional recovery.
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