Open Access
Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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Alginate enhances elongation of early regenerating axons in spinal cord of young rats.
Kazuya Kataoka,Yoshihisa Suzuki,Masaaki Kitada,Tadashi Hashimoto,Hirotomi Chou,Hongliang Bai,Masayoshi Ohta,Sufan Wu,Kyoko Suzuki,Chizuka Ide +9 more
TL;DR: It is suggested that alginate contributed to reducing the barrier composed of connective tissues and reactive astrocytic processes, and served as a scaffold for the outgrowth of regenerating axons and elongation of astroCytic processes.
Journal ArticleDOI
Nerve cell differentiation in vitro
TL;DR: The differentiation of cultured neurons from 4- and 8-day chick spinal ganglia has been studied when the nerve cell bodies rest on plastic, gelatin, glial cells, and heart fibroblasts, and when conditioned media are present.
Journal ArticleDOI
Neuronal Cell Adhesion Molecules and Cytotactin Are Colocalized at the Node of Ranvier
François Rieger,Joanne K. Daniloff,Martine Pinçon-Raymond,Kathryn L. Crossin,Martin Grumet,Gerald M. Edelman +5 more
TL;DR: Findings are consistent with the hypothesis that surface modulation of neuronal CAMs mediated by signals shared between neurons and glia may be necessary for establishing and maintaining the nodes of Ranvier.
Journal ArticleDOI
Role of insulin-like growth factors in peripheral nerve regeneration
D.N. Ishii,G.W. Glazner,S.-F. Pu +2 more
TL;DR: Insulin-like growth factor (IGF) gene expression is correlated with synapse formation during development and regeneration and IGFs are now identified as the first soluble nerve- and muscle-derived neurotrophic factors found to regulate the rate of peripheral nerve regeneration.
Journal ArticleDOI
Regeneration of lesioned rat optic nerve fibers is improved after neutralization of myelin-associated neurite growth inhibitors.
TL;DR: In this article, the authors demonstrate the ability of postnatal rat optic nerve fibers to regenerate within the CNS microenvironment under two conditions: axonal die-back has to be prevented with appropriate neurotrophic factors, and neurite growth inhibitory components, in particular those associated with CNS oligodendrocytes and myelin, have to be inactivated.
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