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Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
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Journal ArticleDOI
Differences in the labeling of axons of passage by wheat germ agglutinin after uptake by cut peripheral nerve versus injections within the central nervous system
TL;DR: Injections of a radiolabeled derivative of wheat germ agglutinin in the subcortical white matter of the cerebral cortex in mice do not give rise to autoradiographic labeling of axon systems coursing through this fiber mass, but exposing the cut-end of mouse tibial nerve to WGA does produce labeling within dorsal root ganglia and the spinal cord.
Journal ArticleDOI
Olfactory Ensheathing Glia: Drivers of Axonal Regeneration in the Central Nervous System?
TL;DR: Olfactory ensheathing glia accompany olfactory growing axons in their entry to the adult mammalian central nervous system (CNS) and their capacity to produce some neurotrophic factors might account for their ability to produce CNS regeneration.
Journal ArticleDOI
Repair of the mammalian spinal cord
TL;DR: Studies on the pathology of the injured spinal cord in relation to the inherent growth capability of CNS neurons as well as recent experimental approaches designed to provide an environment conducive to axonal elongation are reviewed.
Book ChapterDOI
Understanding myelination through studying its evolution.
TL;DR: This chapter studies mechanisms for the adaptation of sophisticated regulation that underlies myelination for animals living under conditions far different from example, without thermoregulation or different osmotic environments.
Journal ArticleDOI
Severed corticospinal axons recover electrophysiologic control of muscle activity after x-ray therapy in lesioned adult spinal cord.
Nurit Kalderon,Zvi Fuks +1 more
TL;DR: The data suggest that recovery of structural continuity is a sufficient condition for the axotomized corticospinal neurons to regain some of their disrupted function in cord regions distal to the lesion site.
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