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Degeneration and regeneration of the nervous system

Santiago Ramón y Cajal
- pp 236-245
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The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).

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Interactions Between Axons and their Sheath Cells

TL;DR: This selective review discusses structural and functional relationships of axons and sheath cells in normal and abnormal nerves and touches on the more complicated relationships involving axons, oligodendrocytes, and other neuroglia in the central nervous system.
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The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory

TL;DR: The discovery of the AT4 receptor subtype, and its facilitory influence upon learning and memory, suggest an important role for the brain RAS in normal cognitive processing and perhaps in the treatment of dysfunctional memory disease states.
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Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs

TL;DR: Clinically, evidence of reduced hippocampal volume in patients with major depressive disorder or other affective disorders and hypothesize that the next generation of antidepressant drugs will, in addition to their effects on known transmitter or second messenger systems, involve either direct or indirect targeting of neurogenic factors.
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The Sympathetic Innervation of the Urinary Bladder and Urethra in the Normal State and After Parasympathetic Denervation at the Spinal Root Level: An Experimental Study in Cats

TL;DR: The innervation of the feline bladder and urethra was studied by a histochemical fluorescence technique and the use of peripheral nerve stimulations in combination with different blocking agents to observe a change in adrenergic innervation.
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Muscle basal lamina: a new graft material for peripheral nerve repair

TL;DR: It is concluded that muscle basal lamina grafts are as effective as nerve autografts for repairing severed rat or rabbit peripheral nerves, and suggested that grafts prepared in this way may prove to be useful for nerve repair in humans.
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