Open Access
Degeneration and regeneration of the nervous system
Santiago Ramón y Cajal
- pp 236-245
Reads0
Chats0
About:
The article was published on 1928-01-01 and is currently open access. It has received 2218 citations till now. The article focuses on the topics: Degeneration (medical) & Regeneration (biology).read more
Citations
More filters
Journal ArticleDOI
Fate of presynaptic afferents to Purkinje cells in the adult nervous mutant mouse: a model to study presynaptic stabilization.
TL;DR: The significance of the persistence of normal looking presynaptic elements long time after deprivation of their postsynaptic targets is discussed in relation to the role that function can play in the stabilization of synaptic contacts.
Journal ArticleDOI
In vivo imaging of dorsal root regeneration: Rapid immobilization and presynaptic differentiation at the CNS/PNS border
Alessandro Di Maio,Andrew Skuba,B. Timothy Himes,Srishiti L. Bhagat,Jung Keun Hyun,Alan Tessler,Derron L. Bishop,Young-Jin Son +7 more
TL;DR: The first in vivo imaging study of DR regeneration is reported, suggesting that axons are neither repelled nor continuously inhibited at the DREZ by growth-inhibitory molecules but are rapidly stabilized as they invade the CNS territory of the D REZ, forming presynaptic terminal endings on non-neuronal cells.
Journal ArticleDOI
Mechanisms of axonal spheroid formation in central nervous system Wallerian degeneration.
TL;DR: Axonal swellings are hallmarks of many neurodegenerative conditions, and data suggest that they are a manifestation of Wallerian-like degeneration in some cases, which may be a more common component mechanism in CNS diseases than previously thought.
Book ChapterDOI
Protein Metabolism in Nerve Cells
TL;DR: The incessant traffic of components from the perikaryon toward the nerve endings accounts for both the maintenance and the plasticity of neural circuits.
Journal ArticleDOI
Adult neurogenesis and hippocampal memory function: new cells, more plasticity, new memories?
TL;DR: Evidence is reviewed showing a strong correlation between certain types of memory functions and adult neurogenesis in the hippocampus, essential to understand the function of neural networks and to develop effective therapies for various cognitive dysfunctions.
Related Papers (5)
Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats
Samuel David,Albert J. Aguayo +1 more
Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors.
Lisa Schnell,Martin E. Schwab +1 more