Dental disease and risk of coronary heart disease and mortality.
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TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
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Journal ArticleDOI
Oral hygiene practices and knowledge among children of age 10-13 years in a private school in Chennai, South India
TL;DR: Repeated studies in the past have pointed out association between oral disease and heart diseases like coronary artery disease and myocardial infarction and the possible mechanism is molecular mimicry on host arteries by antibodies and T-cells produced in response to infection of gum tissues.
Journal ArticleDOI
Periodontal disease and overall health: An update
TL;DR: The relationship of periodontitis to overall health is examined and a light is thrown on recent associations of the disease to systemic conditions.
Editors' Consensus Report The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: Periodontitis and Atherosclerotic Cardiovascular Disease r
Vincent E. Friedewald,Kenneth S. Kornman,James Beck,Robert J. Genco,Allison B. Goldfine,Peter Libby,S. Offenbacher,Paul M. Ridker,Thomas E. Van Dyke,William C. Roberts +9 more
TL;DR: This Editors’ Consensus is sup-ported by an educational grant from Colgate-Palmo-live, Inc., New York, New Jersey, and is based on ameetingoftheauthorsheld inBoston, Massachusetts, on January 9, 2009.
Book ChapterDOI
Chapter 7 – Periodontal Innate Immune Mechanisms Relevant to Atherosclerosis
Salomon Amar,Jacob Al-Hashemi +1 more
TL;DR: Novel mechanisms associated with deregulated inflammation and its consequences in the vasculature have emerged recently and are discussed in the context of periodontal disease and development of pharmacotherapeutics interventions to address these chronic inflammatory diseases.
References
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Association between dental health and acute myocardial infarction.
Kimmo Mattila,M. S. Nieminen,Ville Valtonen,V. P. Rasi,Y. A. Kesäniemi,S. L. Syrjälä,P. S. Jungell,M. Isoluoma,K. Hietaniemi,M. J. Jokinen +9 more
TL;DR: The association between poor dental health and acute myocardial infarction was investigated in two separate case-control studies and remained valid after adjustment for age, social class, smoking, serum lipid concentrations, and the presence of diabetes.
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Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
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TL;DR: The results generally support the previously reported association between C pneumoniae infection and coronary heart disease, and caution should be used in interpreting the basis for this association.
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The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study
TL;DR: Differences were noted in the risk profiles for various manifestations of cardiovascular disease (CVD) that occurred before the age of 65 during the first 30 years of follow-up of the 5070 subjects of the original Framingham cohort, highlighting the need for future studies to distinguish better between those factors that precipitate cardiovascular events and those that relate to the pathogenesis of the underlying atherosclerosis.