Dental disease and risk of coronary heart disease and mortality.
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TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
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Journal ArticleDOI
Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association? A Scientific Statement From the American Heart Association
Peter B. Lockhart,Ann F. Bolger,Panos N. Papapanou,Olusegun Osinbowale,Maurizio Trevisan,Matthew E. Levison,Kathryn A. Taubert,Jane W. Newburger,Heather L. Gornik,Michael H. Gewitz,Walter R. Wilson,Sidney C. Smith,Larry M. Baddour +12 more
TL;DR: Whether available data support an independent association between ASVD and PD and whether PD treatment might modify ASVD risks or outcomes is assessed and mechanistic details of both PD and ASVD relevant to this topic are presented.
Journal ArticleDOI
Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients.
Bruno G. Loos,Jeroen Craandijk,Frans J. Hoek,Paulien M.E. Wertheim-van Dillen,Ubele van der Velden +4 more
TL;DR: periodontitis results in higher systemic levels of CRP, IL-6, and neutrophils, which may increase inflammatory activity in atherosclerotic lesions, potentially increasing the risk for cardiac or cerebrovascular events.
Journal ArticleDOI
Periodontal Diseases: Epidemiology
TL;DR: Although prevalence figures vary with race and geographic region, in most cases, the progression pattern of the disease seems compatible with the retention of a functional dentition throughout life, and most recent data indicate that periodontal disease may confer risk for coronary heart disease and pre-term low birth weight.
Journal ArticleDOI
Periodontal Infections Contribute to Elevated Systemic C-Reactive Protein Level
Barbara Noack,Robert J. Genco,Maurizio Trevisan,Sara G. Grossi,Joseph J. Zambon,Ernesto De Nardin +5 more
TL;DR: The extent of increase in CRP levels in periodontitis patients depends on the severity of the disease after adjusting for age, smoking, body mass index, triglycerides, and cholesterol, which were found to be significant covariates.
Journal ArticleDOI
Periodontal Disease and Coronary Heart Disease Incidence: A Systematic Review and Meta-analysis
TL;DR: Periodontal disease is a risk factor or marker for CHD that is independent of traditional CHD risk factors, including socioeconomic status.
References
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Journal ArticleDOI
Association between dental health and acute myocardial infarction.
Kimmo Mattila,M. S. Nieminen,Ville Valtonen,V. P. Rasi,Y. A. Kesäniemi,S. L. Syrjälä,P. S. Jungell,M. Isoluoma,K. Hietaniemi,M. J. Jokinen +9 more
TL;DR: The association between poor dental health and acute myocardial infarction was investigated in two separate case-control studies and remained valid after adjustment for age, social class, smoking, serum lipid concentrations, and the presence of diabetes.
Journal ArticleDOI
Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
Journal ArticleDOI
Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease
TL;DR: The results generally support the previously reported association between C pneumoniae infection and coronary heart disease, and caution should be used in interpreting the basis for this association.
Journal Article
The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study
TL;DR: Differences were noted in the risk profiles for various manifestations of cardiovascular disease (CVD) that occurred before the age of 65 during the first 30 years of follow-up of the 5070 subjects of the original Framingham cohort, highlighting the need for future studies to distinguish better between those factors that precipitate cardiovascular events and those that relate to the pathogenesis of the underlying atherosclerosis.