Dental disease and risk of coronary heart disease and mortality.
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TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
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Tooth Loss, Apolipoprotein E, and Decline in Delayed Word Recall
TL;DR: Individuals with both risk factors (the allele and fewer teeth) had lower Delayed Word Recall scores at the first examination and declined more quickly compared with participants with neither of these risk factors or with either risk factor alone.
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Beneficial effects of periodontal treatment on metabolic control of hypercholesterolemia
S. Gul Oz,Özlem Fentoğlu,Alpaslan Kilicarslan,Gulay Sain Guven,Mine Durusu Tanrtover,Yasar Aykac,Tumay Sozen +6 more
TL;DR: It is indicated that periodontitis causes changes in total and LDL cholesterol levels and local periodontal treatment resulted in a significant decrease in these markers.
Journal ArticleDOI
Tooth loss and heart disease: findings from the Behavioral Risk Factor Surveillance System.
Catherine A. Okoro,Lina S. Balluz,Paul I. Eke,Umed A. Ajani,Tara W. Strine,Machell Town,George A. Mensah,Ali H. Mokdad +7 more
TL;DR: Tooth loss is associated in a consistent and graded fashion with the self-reported prevalence of heart disease and health promotion counseling should include the prevention and control of cardiovascular disease risk factors and the maintenance of good oral health.
Journal ArticleDOI
Evaluation of gingival crevicular fluid and serum levels of high-sensitivity C-reactive protein in chronic periodontitis patients with or without coronary artery disease.
TL;DR: Serious periodontitis patients with CP and CP + CAD had statistically significant elevations in serum HsCRP levels compared to healthy subjects, however, Hs CRP levels of GCF did not differ from those of the control and CP groups or the Control andCP + CAD groups.
Journal ArticleDOI
Interactions of Porphyromonas gingivalis with host cells: implications for cardiovascular diseases
TL;DR: A potential role for P. gingivalis in several steps involved in atherosclerotic lesion formation is suggested in model systems using human umbilical vein endothelial cells and murine J774 macrophage cell cultures.
References
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Association between dental health and acute myocardial infarction.
Kimmo Mattila,M. S. Nieminen,Ville Valtonen,V. P. Rasi,Y. A. Kesäniemi,S. L. Syrjälä,P. S. Jungell,M. Isoluoma,K. Hietaniemi,M. J. Jokinen +9 more
TL;DR: The association between poor dental health and acute myocardial infarction was investigated in two separate case-control studies and remained valid after adjustment for age, social class, smoking, serum lipid concentrations, and the presence of diabetes.
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Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
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Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease
TL;DR: The results generally support the previously reported association between C pneumoniae infection and coronary heart disease, and caution should be used in interpreting the basis for this association.
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The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study
TL;DR: Differences were noted in the risk profiles for various manifestations of cardiovascular disease (CVD) that occurred before the age of 65 during the first 30 years of follow-up of the 5070 subjects of the original Framingham cohort, highlighting the need for future studies to distinguish better between those factors that precipitate cardiovascular events and those that relate to the pathogenesis of the underlying atherosclerosis.