Dental disease and risk of coronary heart disease and mortality.
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TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
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Periodontitis, cardiovascular disease and pregnancy outcome--focal infection revisited?
Mark Ide,Gerard J. Linden +1 more
TL;DR: The history and supporting theories behind periodontal disease associations, whether clinical studies have been able to confirm these and what this might mean for general practitioners who are questioned on this topic by patients are summarised.
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Periodontitis is associated with cardiovascular diseases: A 13-year study.
Niramol Tiensripojamarn,Attawood Lertpimonchai,Kanoknadda Tavedhikul,Artit Udomsak,Prin Vathesatogkit,Piyamitr Sritara,Orawan Charatkulangkun +6 more
TL;DR: In this article, the Cox proportional hazard regression model was used to estimate hazard ratios (HRs) and showed that severe periodontitis is associated with an increased incidence of coronary heart disease (CHD), independent of established cardiovascular risk factors.
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Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice.
Conor O'Boyle,Michael J. Haley,Eloise Lemarchand,Craig J. Smith,Stuart M. Allan,Joanne E. Konkel,Joanne E. Konkel,Catherine B. Lawrence +7 more
TL;DR: Oral inflammatory disease does not impact acute stroke pathology in terms of severity, determined primarily by infarct volume, and this indicates that, at least in this experimental paradigm, periodontitis alone does not alter acute outcome after cerebral ischemia.
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Association of periodontal and cardiovascular diseases: South-Asian studies 2001-2012.
TL;DR: Empirical and clinical studies from South-Asia validate the global evidence on association of periodontal disease with CVDs, however, there is a need for meticulous research for public health and scientific perspective of the Periodontal andCVDs from North-Asia.
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Cardiovascular drugs-induced oral toxicities: A murky area to be revisited and illuminated.
TL;DR: This review sheds lights on the oral adverse effects pertaining to the clinical use of cardiovascular drugs and an adverse correlation between oral disease and cardiovascular disease has been discussed.
References
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Association between dental health and acute myocardial infarction.
Kimmo Mattila,M. S. Nieminen,Ville Valtonen,V. P. Rasi,Y. A. Kesäniemi,S. L. Syrjälä,P. S. Jungell,M. Isoluoma,K. Hietaniemi,M. J. Jokinen +9 more
TL;DR: The association between poor dental health and acute myocardial infarction was investigated in two separate case-control studies and remained valid after adjustment for age, social class, smoking, serum lipid concentrations, and the presence of diabetes.
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Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
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Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease
TL;DR: The results generally support the previously reported association between C pneumoniae infection and coronary heart disease, and caution should be used in interpreting the basis for this association.
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The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study
TL;DR: Differences were noted in the risk profiles for various manifestations of cardiovascular disease (CVD) that occurred before the age of 65 during the first 30 years of follow-up of the 5070 subjects of the original Framingham cohort, highlighting the need for future studies to distinguish better between those factors that precipitate cardiovascular events and those that relate to the pathogenesis of the underlying atherosclerosis.