Dental disease and risk of coronary heart disease and mortality.
Reads0
Chats0
TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
More filters
Anti-P. gingivalis Response Correlates with Atherosclerosis
TL;DR: In this article, the authors examined the effect of repeated immunizations with either or both of these agents, and to determine if molecular mimicry of bacterial heat-shock protein (HSP), termed GroEL, and host (h) HSP60 was involved.
Journal ArticleDOI
Coronary heart disease and periodontitis -- a case control study in Chilean adults.
Rodrigo López,Marcela Oyarzún,Claudia Carricarte Naranjo,Francisco Cumsille,Mario Ortiz,Vibeke Baelum +5 more
TL;DR: The results demonstrate that CHD and periodontal diseases cluster in the same sections of the population, which is important from a public health point of view.
Journal ArticleDOI
Porphyromonas gingivalis virulence factors and invasion of cells of the cardiovascular system.
TL;DR: Preliminary evidence indicates that an avirulent Salmonella typhimurium strain containing hagA is virulent in mice, and indicates that HagA may be a key virulence factor of Porphyromonas gingivalis.
Journal ArticleDOI
Age-Dependent Associations Between Chronic Periodontitis/Edentulism and Risk of Coronary Heart Disease
Journal ArticleDOI
Non-surgical periodontal therapy lowers serum inflammatory markers: a pilot study.
Syed Akhtar Hussain Bokhari,Ayyaz Ali Khan,Dimitris N. Tatakis,Mohammad Azhar,Mohammad Hanif,Mateen Izhar +5 more
TL;DR: periodontal treatment resulted in significant decreases in BOP and PD and lowered serum inflammatory markers in patients with CHD or NCHD, which may result in a decreased risk for CHD in the treated patients.
References
More filters
Journal ArticleDOI
Association between dental health and acute myocardial infarction.
Kimmo Mattila,M. S. Nieminen,Ville Valtonen,V. P. Rasi,Y. A. Kesäniemi,S. L. Syrjälä,P. S. Jungell,M. Isoluoma,K. Hietaniemi,M. J. Jokinen +9 more
TL;DR: The association between poor dental health and acute myocardial infarction was investigated in two separate case-control studies and remained valid after adjustment for age, social class, smoking, serum lipid concentrations, and the presence of diabetes.
Journal ArticleDOI
Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
Journal ArticleDOI
Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease
TL;DR: The results generally support the previously reported association between C pneumoniae infection and coronary heart disease, and caution should be used in interpreting the basis for this association.
Journal Article
The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study
TL;DR: Differences were noted in the risk profiles for various manifestations of cardiovascular disease (CVD) that occurred before the age of 65 during the first 30 years of follow-up of the 5070 subjects of the original Framingham cohort, highlighting the need for future studies to distinguish better between those factors that precipitate cardiovascular events and those that relate to the pathogenesis of the underlying atherosclerosis.