Dental disease and risk of coronary heart disease and mortality.
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TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
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Journal ArticleDOI
Periodontal Disease and Cardiovascular Disease
TL;DR: It is suggested that periodontal disease, once established, provides a biological burden of endotoxin (lipopolysaccharide) and inflammatory cytokines (especially TxA2, IL-1β, PGE2, and TNF-α) which serve to initiate and exacerbate atherogenesis' and thromboembolic events.
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Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host.
Weerapan Khovidhunkit,Min Sun Kim,Riaz A. Memon,Judy K. Shigenaga,Arthur H. Moser,Kenneth R. Feingold,Carl Grunfeld +6 more
TL;DR: APR-induced alterations initially protect the host from the harmful effects of bacteria, viruses, and parasites, however, if prolonged, these changes in the structure and function of lipoproteins will contribute to atherogenesis.
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Identification of periodontal pathogens in atheromatous plaques.
TL;DR: periodontal pathogens are present in atherosclerotic plaques where, like other infectious microorganisms such as C. pneumoniae, they may play a role in the development and progression of atherosclerosis leading to coronary vascular disease and other clinical sequelae.
Journal ArticleDOI
Periodontal diseases: pathogenesis.
TL;DR: The mechanism of action of possible risk factors, such as smoking and diabetes on the host, and the evidence that host modulating agents will be effective in prevention or treatment of periodontal diseases are studied.
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Systemic Diseases Caused by Oral Infection
TL;DR: The purpose of this review is to evaluate the current status of oral infections, especially periodontitis, as a causal factor for systemic diseases.
References
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Risk factors for coronary heart disease mortality among persons with diabetes
Frank DeStefano,Earl S. Ford,Jeffrey Newman,John M. Stevenson,Scott F. Wetterhall,Robert F. Anda,Frank Vinicor +6 more
TL;DR: Risk factors for coronary heart disease mortality were similar among those with and those without diabetes: Cigarette smoking and high blood pressure each were associated with about a twofold increase in risk.
Decayed, missing, and filled teeth among persons 1-74 years, United States, 1971-74; estimates of tooth loss : decayed, missing, and filled (DMF) permanent teeth and decayed, nonfunctional-carious and filled (def) primary teeth among persons 1-74 years in 1971-74 by sociodemographic characteristics, showing comparison with national estimates for 1960-1970
Clair R. Harvey,James E. Kelly +1 more
TL;DR: This report from the National Center for Health Statistics presents estimates of decayed, missing, and filled (DMF) permanent teeth among persons 1-74 years of age by age, race, sex, and selected demographic characteristics.
Journal ArticleDOI
Dental health and acute myocardial infarction.
TL;DR: All health districts should consider in their performance indicators for the elderly how many baths and simple toenail cutting services they provide and whether a service provided under health visiting management would not answer any unmet need cost effectively.
Journal ArticleDOI
Audit of 26 years of obstetrics in general practice.
G. N. Marsh,D. M. Channing +1 more
TL;DR: An audit of 1223 consecutive obstetric deliveries over 26 years was carried out with standard clinical records, finding a "steady state" was achieved during the final 11 years in which 73% of women booked to be delivered by their general practitioner, 64% were admitted to the general practitioner unit, and 54% were delivered bytheir general practitioner.
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Dental health and acute myocardial infarction: Author's reply
TL;DR: Design flaws remain unconvinced of the clinical relevance of the observed association between poor dental health and myocardial infarction, which can probably be explained by study bias or, more possibly, by the known association of low social class with both disorders.