Dental disease and risk of coronary heart disease and mortality.
Reads0
Chats0
TLDR
Dental disease is associated with an increased risk of coronary heart disease, particularly in young men, and may be a more general indicator of personal hygiene and possibly health care practices.Abstract:
OBJECTIVE--To investigate a reported association between dental disease and risk of coronary heart disease. SETTING--National sample of American adults who participated in a health examination survey in the early 1970s. DESIGN--Prospective cohort study in which participants underwent a standard dental examination at baseline and were followed up to 1987. Proportional hazards analysis was used to estimate relative risks adjusted for several covariates. MAIN OUTCOME MEASURES--Incidence of mortality or admission to hospital because of coronary heart disease; total mortality. RESULTS--Among all 9760 subjects included in the analysis those with periodontitis had a 25% increased risk of coronary heart disease relative to those with minimal periodontal disease. Poor oral hygiene, determined by the extent of dental debris and calculus, was also associated with an increased incidence of coronary heart disease. In men younger than 50 years at baseline periodontal disease was a stronger risk factor for coronary heart disease; men with periodontitis had a relative risk of 1.72. Both periodontal disease and poor oral hygiene showed stronger associations with total mortality than with coronary heart disease. CONCLUSION--Dental disease is associated with an increased risk of coronary heart disease, particularly in young men. Whether this is a causal association is unclear. Dental health may be a more general indicator of personal hygiene and possibly health care practices.read more
Citations
More filters
Journal ArticleDOI
Evaluation of the relation between anemia and periodontitis by estimation of blood parameters: A cross-sectional study
TL;DR: The treatment ofperiodontitis can lead to an improvement in hematocrit and other related blood parameters in chronic generalized periodontitis patients with anemia, providing evidence that periodontritis like other chronic diseases may also cause anemia.
Journal Article
Is periodontal disease a risk factor for coronary artery disease (CAD)
TL;DR: Current evidence is insufficient to justify treatment of dental infections to arrest or reverse CAD or other systemic conditions (e.g., diabetes mellitus, stroke or adverse outcomes of pregnancies).
Journal ArticleDOI
Optimal design of thiostrepton-derived thiopeptide antibiotics and their potential application against oral pathogens
TL;DR: In this article, a quinaldic acid (QA)-modified siomycin (SIO) derivative, 5′-fluoro-SIO, with an unanticipated improvement in water solubility was generated.
Journal ArticleDOI
Oral health and the role of the geriatrician.
Journal Article
Role of Periodontal Infection in Cardiovascular Disease: a Current Perspective
TL;DR: Following periodontal therapy, studies have shown reduction in the levels of pro-inflammatory cytokines and acute phase reactants, enhancement of endothelial function and lowered risk for future cardiovascular events.
References
More filters
Journal ArticleDOI
Association between dental health and acute myocardial infarction.
Kimmo Mattila,M. S. Nieminen,Ville Valtonen,V. P. Rasi,Y. A. Kesäniemi,S. L. Syrjälä,P. S. Jungell,M. Isoluoma,K. Hietaniemi,M. J. Jokinen +9 more
TL;DR: The association between poor dental health and acute myocardial infarction was investigated in two separate case-control studies and remained valid after adjustment for age, social class, smoking, serum lipid concentrations, and the presence of diabetes.
Journal ArticleDOI
Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study.
Pekka Saikku,M. Leinonen,L. Tenkanen,E Linnanmäki,M. R. Ekman,Vesa Manninen,Matti Mänttäri,M H Frick,J K Huttunen +8 more
TL;DR: The results suggest that chronic C. pneumoniae infection may be a significant risk factor for the development of coronary heart disease.
Journal ArticleDOI
Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease
TL;DR: The results generally support the previously reported association between C pneumoniae infection and coronary heart disease, and caution should be used in interpreting the basis for this association.
Journal Article
The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study
TL;DR: Differences were noted in the risk profiles for various manifestations of cardiovascular disease (CVD) that occurred before the age of 65 during the first 30 years of follow-up of the 5070 subjects of the original Framingham cohort, highlighting the need for future studies to distinguish better between those factors that precipitate cardiovascular events and those that relate to the pathogenesis of the underlying atherosclerosis.