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Journal ArticleDOI

Direct inguinal herniation in men: a disease of collagen.

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This article is published in Journal of Surgical Research.The article was published on 1974-12-01. It has received 149 citations till now. The article focuses on the topics: Hernia.

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Citations
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Journal ArticleDOI

[Historic analysis of complex incisional hernia: to an understanding of the double prosthetic repair technique].

TL;DR: An historical review of the prosthetic treatment of incisional hernias is carried out, trying to understand and apply the basic principles of the treatment of all incisions to the repair with a double mesh.
Journal ArticleDOI

Systemic hernial disease protects against cancer: an hypothesis.

TL;DR: Damage to the colonic ECM from hernial disease is conducive to diverticulosis, but hostile for cancer, suggesting that certain genes prevent stromal malignancy by influencing the microenvironment to stop epithelia from becoming cancerous.
Journal ArticleDOI

Etiology and biomechanics of hernial sac formation.

TL;DR: It is proposed that the herniation process can be viewed as a biomechanically unstable phenomenon in the light of the present model, which incorporates both material and geometric nonlinearities by considering deformation of circular membrane under internal fluid pressure.
Book ChapterDOI

The Role of Collagen in Hernia Genesis

TL;DR: The aim of this chapter is to give an overview of the literature on the role of collagen in hernia genesis, with a focus on biomechanical tissue features.
References
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Journal ArticleDOI

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.

TL;DR: Method has been applied to a study of hydroxyproline distribution in cell particulates, tissue fluids, and purified plant and animal proteins, and significant amounts of hydroXYproline were found in crystalline preparations of pepsin, elastase.
Journal ArticleDOI

Defective collagen synthesis in inguinal herniation

TL;DR: It is suggested that the cause of herniation in the adult lies in a reduced collagen synthesis by the fibroblasts, thus rendering the abdominal aponeuroses weaker.
Journal ArticleDOI

The effect of chelating agents on collagen interfibrillar matrix interactions in connective tissue.

TL;DR: It is suggested that metal ions play a part in the interaction of collagen fibrils and the interfibrillar matrix in tendon, indicating the chemical purity of the collagen.
Journal ArticleDOI

Attenuation of the rectus sheath in inguinal herniation.

TL;DR: Results indicate that in inguinal herniation the rectus sheath unrelated to the defect is thinner than normal, and a patent processus vaginalis allows herniated with less atrophy than in direct defects.
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