Journal ArticleDOI
Direct inguinal herniation in men: a disease of collagen.
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This article is published in Journal of Surgical Research.The article was published on 1974-12-01. It has received 149 citations till now. The article focuses on the topics: Hernia.read more
Citations
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Journal ArticleDOI
The role of matrix metalloproteinases in the pathogenesis of abdominal wall hernias.
TL;DR: Current evidence suggests a strong correlation between MMP‐2 and direct inguinal hernia, while the role of this MMP in indirect, incisional and recurrent hernias has not been completely elucidated yet.
Journal ArticleDOI
The inheritance of groin hernia: a systematic review
TL;DR: The literature on the inheritance of groin hernias indicates that groin hernia is most likely an inherited disease; however, neither the extent of familial accumulation nor a clear inheritance pattern has yet been found.
Journal ArticleDOI
Effect of lifestyle, gender and age on collagen formation and degradation
TL;DR: Clinical evidence produced over the past few decades indicates that a modern lifestyle factor, such as smoking, together with biologic characteristics, like old age and male gender, are risk factors for abdominal wall hernia and recurrence.
Journal ArticleDOI
Role of biomarkers in incisional hernias.
J.R. Salameh,Ladawn M Talbott,Warren L. May,Bashar Gosheh,Parminder J. S. Vig,D. Olga McDaniel +5 more
TL;DR: Reduced collagen I/III and MMP-1/MMP-2 ratios in IH might be consequence of the biological activities between key elements participating in the development of IH after laparotomies, and the potential role of MMP–specific inhibitors in preventing IH is of significance for future studies.
Journal ArticleDOI
Etiology of inguinal hernia: ultrastructure of rectus sheath revisited.
TL;DR: The theory linking connective tissue alterations with the etiology of hernia, and stating that these alterations include connectives tissue at locations distant from the hernia site as well, is supported, as the rectus sheath itself does not form a hernial defect.
References
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Journal ArticleDOI
The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
TL;DR: Method has been applied to a study of hydroxyproline distribution in cell particulates, tissue fluids, and purified plant and animal proteins, and significant amounts of hydroXYproline were found in crystalline preparations of pepsin, elastase.
Journal ArticleDOI
Defective collagen synthesis in inguinal herniation
TL;DR: It is suggested that the cause of herniation in the adult lies in a reduced collagen synthesis by the fibroblasts, thus rendering the abdominal aponeuroses weaker.
Journal ArticleDOI
The effect of chelating agents on collagen interfibrillar matrix interactions in connective tissue.
TL;DR: It is suggested that metal ions play a part in the interaction of collagen fibrils and the interfibrillar matrix in tendon, indicating the chemical purity of the collagen.
Journal ArticleDOI
Attenuation of the rectus sheath in inguinal herniation.
Raymond C. Read,Raymond C. Read +1 more
TL;DR: Results indicate that in inguinal herniation the rectus sheath unrelated to the defect is thinner than normal, and a patent processus vaginalis allows herniated with less atrophy than in direct defects.
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Metastatic emphysema a mechanism for acquiring inguinal herniation
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