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Journal ArticleDOI

Direct inguinal herniation in men: a disease of collagen.

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This article is published in Journal of Surgical Research.The article was published on 1974-12-01. It has received 149 citations till now. The article focuses on the topics: Hernia.

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Citations
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Mesh repair of hernias of the abdominal wall

TL;DR: A randomized clinical trial to compare mesh and non-mesh repair for inguinal hernias is performed and the preferential method of hernia repair is discussed in an editorial.
Book ChapterDOI

Epidemiology and Etiology of Primary Groin Hernias

TL;DR: There is an unmet need for groin hernia surgery with many patients being denied access by their family doctor and once referred, surgeons seem to act as gatekeepers and may indeed “cherry-pick.”
Book ChapterDOI

The Biology of Hernia Formation

TL;DR: In this article, a decreased type I to III collagen ratio has been demonstrated in the fascia of patients with inguinal or incisional hernias, leading to thinner collagen fibers with less strength.
Journal ArticleDOI

Measurement of hydroxyproline and nitric oxide, and comparison of sac fluid acidity in different inguinal pathologies.

TL;DR: Hydxyproline and nitric oxide pathways do not seem to be responsible for the different characteristics of inguinal diseases, however, differences in the acidity of sac fluid may be evidence of the different mechanisms of hernia and hydrocele formation.
Journal ArticleDOI

Impact of age on groin hernia profiles observed during laparoscopic transabdominal preperitoneal hernia repair

TL;DR: The multiple occurrence of groin hernias, either unilaterally or bilaterally, was a clinical feature in the elderly, observed during laparoscopic transabdominal preperitoneal TAPP hernia repair.
References
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Journal ArticleDOI

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.

TL;DR: Method has been applied to a study of hydroxyproline distribution in cell particulates, tissue fluids, and purified plant and animal proteins, and significant amounts of hydroXYproline were found in crystalline preparations of pepsin, elastase.
Journal ArticleDOI

Defective collagen synthesis in inguinal herniation

TL;DR: It is suggested that the cause of herniation in the adult lies in a reduced collagen synthesis by the fibroblasts, thus rendering the abdominal aponeuroses weaker.
Journal ArticleDOI

The effect of chelating agents on collagen interfibrillar matrix interactions in connective tissue.

TL;DR: It is suggested that metal ions play a part in the interaction of collagen fibrils and the interfibrillar matrix in tendon, indicating the chemical purity of the collagen.
Journal ArticleDOI

Attenuation of the rectus sheath in inguinal herniation.

TL;DR: Results indicate that in inguinal herniation the rectus sheath unrelated to the defect is thinner than normal, and a patent processus vaginalis allows herniated with less atrophy than in direct defects.
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