Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade
TLDR
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS).Abstract:
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.read more
Citations
More filters
Book ChapterDOI
Reactivity of P–H Group of H-Phosphinic Acid and Its Derivatives
TL;DR: The cross-coupling and dehydrogenative coupling reactions in the future will be key motif for scientists working in the field of phosphorus chemistry and open new chemical routes for polymer modification and for preparation of new materials.
Journal Article
Efficient Synthesis of Dihydropyrimidine and Amidoalkyl Naphthol Derivatives Using Zinc Chloride-Based Deep Eutectic Systems as Solvent & Catalyst
TL;DR: In this paper, a one-pot synthesis of Dihydropyrimidine and amidoalkyl naphthol derivatives using ZnCl2/urea and ZnCL2/acetamide deep eutectic systems as reaction medium and homogeneous catalyst is presented.
Journal ArticleDOI
2,4-5-Trisubstituted Thiazole Building Blocks by a Novel Multi-Component Reaction.
TL;DR: In this article, a multi-component reaction (MCR) of oxo-components, primary amines, thiocarboxylic acids and 3-bromo-2-isocyanoacrylates yielding 2,4,5 trisubstituted thiazole building blocks is described.
References
More filters
Book
Comprehensive Heterocyclic Chemistry II
TL;DR: In this article, the CHEC III is organized in 15 volumes and closely follows the organization used in the previous edition: Volumes 1 and 2: Cover respectively three and four-membered heterocycles, together with all fused systems containing a three- or four-measured heterocyclic ring.
Journal ArticleDOI
Natural product synthesis using multicomponent reaction strategies.
B. Barry Touré,Dennis G. Hall +1 more
TL;DR: The preparation of urea by Wöhler constituted a landmark achievement in organic chemistry, and it laid the ground for the early days of target-oriented organic synthesis, a task deemed inconceivable by early practitioners.
Journal ArticleDOI
A Planning Strategy for Diversity‐Oriented Synthesis
TL;DR: Although the distinct goals of DOS do not permit the application of retrosynthetic concepts and thinking, these foundations are being built on, by using parallel logic, to develop a complementary procedure known as forward-Synthetic analysis, which facilitates synthetic planning, communication, and teaching in this evolving discipline.
Journal ArticleDOI
Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity
TL;DR: An overview of general strategies that allow the design of novel multicomponent reactions is presented and the challenges and opportunities for the future are discussed.
Journal ArticleDOI
Strategies for Innovation in Multicomponent Reaction Design
TL;DR: This Account provides several examples that illustrate the use of SRR with known MCRs as starting points for synthetic innovation in this area, and explores strategies for engineering improvements into known M CRs, either by increasing the dimensionality, broadening the scope of useful input structures, or both.