Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade
TLDR
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS).Abstract:
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.read more
Citations
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References
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Journal ArticleDOI
Microwave multicomponent synthesis.
TL;DR: This review will explore the advances and advantages in microwave multicomponent synthesis (MMS) that have been achieved over the last five years.
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The reaction of (N-isocyanimino)triphenylphosphorane with dialkyl acetylenedicarboxylates in the presence of 1,3-diphenyl-1,3-propanedione: a novel three-component reaction for the stereoselective synthesis of dialkyl (Z)-2-(5,7-diphenyl-1,3,4-oxadiazepin-2-yl)-2-butenedioates
TL;DR: In this article, the reaction of dialkyl (Z)-2-(5,7-diphenyl-1,3,4-oxadiazepin-2-yl)-2-butenedioates with Nisocyaniminotriphenylphosphorane was shown to be completely stereoselective.
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Synthesis of highly functionalized bis(4H-chromene) and 4H-benzo[g]chromene derivatives via an isocyanide-based pseudo-five-component reaction.
TL;DR: The reactive intermediates generated by the addition of alkyl, aryl, and alicyclic isocyanides to dialkyl acetylenedicarboxylates were trapped to produce highly functionalized bis(4H-chromene)- and 4H-benzo[g]chromene-3,4-dicar boxylate derivatives in fairly good yields in CH(3)CN at room temperature.
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A grinding-induced catalyst- and solvent-free synthesis of highly functionalized 1,4-dihydropyridines via a domino multicomponent reaction
Atul Kumar,Siddharth Sharma +1 more
TL;DR: A grinding-induced catalyst and solvent-free domino multicomponent reaction for the synthesis of 1,4-dihydropyridines has been developed using aldehydes, amines, DEAD (diethyl acetylenedicarboxylate), and malononitrile/ethyl cyanoacetate as discussed by the authors.
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Three-component synthesis of polysubstituted pyrroles from α-diazoketones, nitroalkenes, and amines.
TL;DR: Polysubstituted pyrroles are regiospecifically synthesized via the copper-catalyzed three-component reaction of α-diazoketones, nitroalkenes, and amines under aerobic conditions.