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Open AccessJournal ArticleDOI

Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade

Heiner Eckert
- 20 Jan 2012 - 
- Vol. 17, Iss: 1, pp 1074-1102
TLDR
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS).
Abstract
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.

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Citations
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Unravelling the labyrinth of palladium-catalysed reactions involving isocyanides

TL;DR: This tutorial review focuses on Isocyanides various applications in chemical synthesis, and the wide range of systems that can be efficiently prepared using this strategy are documented.
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Multicomponent mechanochemical synthesis

TL;DR: Multicomponent reactions promoted by mechanical energy are critically reviewed and new ideas are proposed to improve the understanding of these reactions.
References
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Journal ArticleDOI

Recent progress of isocyanide-based multicomponent reactions in Iran.

TL;DR: The aim of this review is to provide an overview of the contributions and recent advances made by Iranian scientists in the field of isocyanide-based reactions between 1999 and 2009.
Journal ArticleDOI

Recent Progress in Three-Component Reactions. An Update

TL;DR: Three-component reactions have emerged as useful methods because the combination of three components to generate new products in a single step is extremely economical, among the multi-component rea... as discussed by the authors.
Journal ArticleDOI

Recent application of isocyanides in synthesis of heterocycles

TL;DR: In this article, the recent isocyanide-based synthesis of various types of heterocycles is reviewed, and 98 references are provided, including 98 references from the same authors.
Journal ArticleDOI

1,3-Dicarbonyl compounds in stereoselective domino and multicomponent reactions

TL;DR: The 1,3-dicarbonyl (1D) compound as mentioned in this paper is an exceptional platform for 1D organic synthesis due to the presence of four contiguous reaction sites, which allows cascades of elemental steps from simple substrates.
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