Diversity Oriented Syntheses of Conventional Heterocycles by Smart Multi Component Reactions (MCRs) of the Last Decade
TLDR
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS).Abstract:
A collection of smart multicomponent reactions (MCRs) with continuative post condensation cyclizations (PCCs) is presented to construct conventional three- to seven-membered heterocyclic compounds in diversity oriented syntheses (DOS). These will provide a high degree of applying economical and ecological advantages as well as of practicability. Water, ionic liquids, and solvent-less syntheses as well as use of various forms of energy as microwave and ultrasonic irradiation are examined and discussed.read more
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References
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New MCRs: The First 4-Component Reaction Leading to 2,4-Disubstituted Thiazoles.
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One-pot, three-component, highly diastereoselective metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines
Luis Crovetto,Ramon Rios +1 more
TL;DR: In this paper, an extremely efficient, highly diastereoselective, metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines is described.
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The Role of Isocyanides in the Synthesis of β‐Lactam Antibiotics and Related Compounds
Heiner Eckert,Ivar Ugi +1 more
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One‐Pot, Three‐Component, Highly Diastereoselective Metal‐Free Synthesis of 2,3,4,5‐Tetrasubstituted Pyrrolidines.
Luis Crovetto,Ramon Rios +1 more
TL;DR: In this article, an extremely efficient, highly diastereoselective, metal-free synthesis of 2,3,4,5-tetrasubstituted pyrrolidines is described.