Early detection and intervention evaluation for people at risk of psychosis: multisite randomised controlled trial
Anthonty P. Morrison,Paul French,Suzanne L. K. Stewart,Max Birchwood,David Fowler,Andrew Gumley,Peter B. Jones,Richard P. Bentall,Shôn Lewis,Graham K. Murray,Paul Patterson,Kat Brunet,Jennie Conroy,Sophie Parker,T Reilly,Rory Byrne,Linda Davies,Graham Dunn +17 more
TLDR
Cognitive therapy plus monitoring did not significantly reduce transition to psychosis or symptom related distress but reduced the severity of psychotic symptoms in young people at high risk of psychosis.Abstract:
Objective To determine whether cognitive therapy is effective in preventing the worsening of emerging psychotic symptoms experienced by help seeking young people deemed to be at risk for serious conditions such as schizophrenia.read more
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Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide
Tammy Hoffmann,Paul Glasziou,Isabelle Boutron,Ruairidh Milne,Rafael Perera,David Moher,Douglas G. Altman,Virginia Barbour,Helen Macdonald,Marie Johnston,Sarah E Lamb,Mary Dixon-Woods,Peter McCulloch,Jeremy C Wyatt,An-Wen Chan,Susan Michie +15 more
TL;DR: The TIDieR checklist and guide should improve the reporting of interventions and make it easier for authors to structure accounts of their interventions, reviewers and editors to assess the descriptions, and readers to use the information.
Journal ArticleDOI
Comorbid Depressive and Anxiety Disorders in 509 Individuals With an At-Risk Mental State: Impact on Psychopathology and Transition to Psychosis
TL;DR: The ARMS patients are characterized by high prevalence of anxiety and depressive disorders in addition to their attenuated psychotic symptoms, which may reflect core emotional dysregulation processes and delusional mood in prodromal psychosis.
Journal ArticleDOI
Risk of Mental Illness in Offspring of Parents With Schizophrenia, Bipolar Disorder, and Major Depressive Disorder: A Meta-Analysis of Family High-Risk Studies
TL;DR: Offspring of parents with SMI are at increased risk for a range of psychiatric disorders and one third of them may develop a SMI by early adulthood.
Journal ArticleDOI
Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology:
TL;DR: These guidelines from the British Association for Psychopharmacology address the scope and targets of pharmacological treatment for schizophrenia, and cover the pharmacological management and treatment of schizophrenia across the various stages of the illness.
Journal ArticleDOI
EPA guidance on the early intervention in clinical high risk states of psychoses.
Frauke Schultze-Lutter,Chantal Michel,Stefanie Julia Schmidt,Benno Karl Edgar Schimmelmann,Nadja P. Maric,Raimo K. R. Salokangas,Anita Riecher-Rössler,M. van der Gaag,Merete Nordentoft,Andrea Raballo,Anna Meneghelli,Max Marshall,Anthony P. Morrison,Stephan Ruhrmann,Joachim Klosterkötter +14 more
TL;DR: In this article, the authors provided evidence-based recommendations on early intervention in clinical high risk (CHR) states of psychosis, assessed according to the EPA guidance on early detection, derived from a meta-analysis of current empirical evidence on the efficacy of psychological and pharmacological interventions in CHR samples.
References
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Book
Statistical Analysis with Missing Data
TL;DR: This work states that maximum Likelihood for General Patterns of Missing Data: Introduction and Theory with Ignorable Nonresponse and large-Sample Inference Based on Maximum Likelihood Estimates is likely to be high.
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Specification Tests in Econometrics
TL;DR: In this article, the null hypothesis of no misspecification was used to show that an asymptotically efficient estimator must have zero covariance with its difference from a consistent but asymptonically inefficient estimator, and specification tests for a number of model specifications in econometrics.
Journal ArticleDOI
Statistical Analysis With Missing Data
TL;DR: Generalized Estimating Equations is a good introductory book for analyzing continuous and discrete correlated data using GEE methods and provides good guidance for analyzing correlated data in biomedical studies and survey studies.
Journal ArticleDOI
The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.
TL;DR: The history, rationale, and development of the Structured Clinical Interview for DSM-III-R (SCID) is described, which is a semistructured interview for making the major Axis I DSM- III-R diagnoses.
Journal ArticleDOI
Development and validation of measures of social phobia scrutiny fear and social interaction anxiety
TL;DR: The Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) as mentioned in this paper are two companion measures for assessing social phobia fears, which are developed and validated for clinical and research applications.