Journal ArticleDOI
Engineering of a dual-modal phototherapeutic nanoplatform for single NIR laser-triggered tumor therapy.
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TLDR
In this article, a dual-modal phototherapeutic nanoplatform that achieved both photodynamic therapy (PDT) and photothermal therapy (PTT) under single NIR laser (660-nm) irradiation for chlorin e6 (Ce6) and copper sulfide (CuS) nanoparticles (NPs) is presented.About:
This article is published in Journal of Colloid and Interface Science.The article was published on 2021-07-15. It has received 85 citations till now. The article focuses on the topics: Photothermal therapy.read more
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Dually Enhanced Phototherapy by Gambogic Acid and Hyperthemia-Activated Chemotherapy for Synergistic Breast Cancer Treatment
Yuhan Wang,Chunyan Yue,Mengyao Zhang,Dazhao Li,Tao Xu,Mengying He,Mengyuan Wang,Yanan Zhao,Zi-Mian Ni,Feng Zhi,Yiqiao Hu,Dawei Ding +11 more
TL;DR: In this article , a phase change material (PCM)-based nanoplatform co-delivering paclitaxel (PTX), IR780 and gambogic acid (GA) was developed via a facile method to achieve chemotherapy synergized by duallyenhanced phototherapy of breast cancers.
Journal ArticleDOI
pH-responsive and targeted delivery of rutin for breast cancer therapy via folic acid-functionalized carbon dots
Neeraj Tejwan,Pritam Sadhukhan,Anirudh Sharma,Th. Abhishek Singh,Madushmita Hatimuria,Ashok Pabbathi,Joydeep Das,Parames C. Sil +7 more
TL;DR: In this article , the authors have synthesized carbon dots from red Korean ginseng, and modified further with folic acid (FA) for the targeted and controlled delivery of a natual flavonoid, rutin (RUT), which showed a dose-dependent (10-50 μg/mL) cytotoxicity in MCF-7 cells and caused apoptotic cell death by inducing oxidative stress and mitochondrial damage.
Journal ArticleDOI
Recent Advancements of Stimuli-Responsive Targeted Liposomal Formulations for Cancer Drug Delivery
TL;DR: A review of stimuli-sensitive liposomal drug delivery systems can be found in this article , where stimuli-responsive liposomes are designed to implement either exogenous (temperature, light, and magnetic field) or endogenous (pH changes, enzymatic triggers or redox potential) approaches.
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Reduction-responsive worm-like nanoparticles for synergistic cancer chemo-photodynamic therapy
TL;DR: Wang et al. as mentioned in this paper developed curcumin-loaded reduction-responsive prodrug nanoparticles of new indocyanine green (Cur@IR820-ss-PEG) for synergistic cancer chemo-photodynamic therapy.
Journal ArticleDOI
A hybrid metal-organic framework nanomedicine-mediated photodynamic therapy and hypoxia-activated cancer chemotherapy.
TL;DR: In this paper , a hybrid nanomedicine that activated chemotherapy by inducing hypoxia, which synergized with photodynamic therapy (PDT) to promote antitumor outcomes, was presented.
References
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Journal ArticleDOI
Nanotechnology for Multimodal Synergistic Cancer Therapy
TL;DR: In this review, state-of-the-art studies concerning recent advances in nanotechnology-mediated multimodal synergistic therapy will be systematically discussed, with an emphasis on the construction of multifunctional nanomaterials for realizing bimodal and trimodal synergy therapy.
Journal ArticleDOI
Photodynamic therapy - mechanisms, photosensitizers and combinations.
Stanisław Kwiatkowski,Bartosz Knap,Dawid Przystupski,Jolanta Saczko,Ewa Kędzierska,Karolina Knap-Czop,Jolanta Kotlinska,Olga Michel,Krzysztof Kotowski,Julita Kulbacka +9 more
TL;DR: The object of this review is the anticancer application of PDT, its advantages and possible modifications to potentiate its effects, and the use of nanoparticles enables achievement a targeted method which is focused on specific receptors, and, as a result, increases the selectivity of the photodynamic therapy.
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Photothermally Enhanced Photodynamic Therapy Delivered by Nano-Graphene Oxide
TL;DR: It is shown that the photothermal effect of graphene can be utilized to promote the delivery of Ce6 molecules by mild local heating when exposed to a near-infrared laser at a low power density, further enhancing the PDT efficacy against cancer cells.
Journal ArticleDOI
Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy.
Emma S. Nyman,Paavo H. Hynninen +1 more
TL;DR: A thorough survey of the photophysical and chemical properties of the developed tetrapyrrolic photosensitizers for PDT, with special attention to the singlet-oxygen yield (PhiDelta) of each photoensitizer, because it is one of the most important photodynamic parameters in PDT.
Journal ArticleDOI
Copper sulfide nanoparticles for photothermal ablation of tumor cells
TL;DR: Owing to their unique optical property, small size, low cost of production and low cytotoxicity, CuS nanoparticles are promising new nanomaterials for cancer photothermal ablation therapy.