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Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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Service Delivery Models to Maximize Quality of Life for Older People at the End of Life: A Rapid Review

TL;DR: A comprehensive synthesis of evidence regarding service delivery models that optimize the quality of life (QoL) for older people at the end of life across health, social, and welfare services worldwide is provided.
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Feeling lonely in an unfamiliar place: older people's experiences of life close to death in a nursing home.

TL;DR: It is important to find ways to support older people's wellbeing and identity near death to be able to meet older people as they are and respect them as human beings in their transitions, before, during and after the move to a nursing home.
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Development of a six-month prognostic index in patients with advanced chronic medical conditions: the PALIAR score.

TL;DR: The PALIAR score is a precise and reliable tool for identifying the end-of-life trajectory in patients with advanced medical diseases and its sensitivity, specificity, and positive and negative predictive values at 180 days were high.
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Polypharmacy and specific comorbidities in university primary care settings.

TL;DR: In this paper, the authors measured the prevalence of polypharmacy and inappropriate prescribing, and assessed the association with specific comorbidities, including adverse events and multimorbidity.
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What Is the Impact of Physical Activity and Physical Function on the Development of Multimorbidity in Older Adults Over Time? A Population-Based Cohort Study.

TL;DR: Results show that physical function is associated with the development and worsening of multimorbidity over time, and support the recent National Institute for Health & Care Excellence Guidance on multimOrbidity that suggests that patients with multimor bidity and reduced gait speed should be identified and targeted for interventions to improve health outcomes.
References
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Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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