Journal ArticleDOI
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.About:
This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.read more
Citations
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Multimorbidity—older adults need health care that can count past one
TL;DR: The health-care needs of older people with multimorbidity, and the extent to which these needs are met, are sharp exemplars of the challenges faced by health- Care systems across the world in the 21st century.
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Prevalence of Multimorbidity in a Geographically Defined American Population: Patterns by Age, Sex, and Race/Ethnicity
Walter A. Rocca,Cynthia M. Boyd,Brandon R. Grossardt,William V. Bobo,Lila J. Finney Rutten,Véronique L. Roger,Jon O. Ebbert,Terry M. Therneau,Barbara P. Yawn,Barbara P. Yawn,Jennifer L. St. Sauver +10 more
TL;DR: Multimorbidity is common in the general population; it increases steeply with older age, has different patterns in men and women, and varies by race/ethnicity.
Journal ArticleDOI
Multimorbidity and functional impairment-bidirectional interplay, synergistic effects and common pathways
Amaia Calderón-Larrañaga,Davide L. Vetrano,Davide L. Vetrano,Luigi Ferrucci,Stewart W Mercer,Alessandra Marengoni,Graziano Onder,Maria Eriksdotter,Laura Fratiglioni +8 more
TL;DR: Identifying modifiable risk factors and pathways common to multimorbidity and functional impairment could aid in the design of interventions to delay, prevent or alleviate age‐related health deterioration; this review provides an overview of knowledge gaps and future directions.
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Appropriate Polypharmacy and Medicine Safety: When Many is not Too Many
TL;DR: It is now recognised that the prescribing of ‘many’ medicines can be entirely appropriate in patients with several chronic conditions and that the risks of adverse drug events that have been associated with polypharmacy may be greatly reduced when patients’ clinical context is taken into consideration.
Journal ArticleDOI
Do patients have worse outcomes in heart failure than in cancer? A primary care-based cohort study with 10-year follow-up in Scotland.
Mamas A. Mamas,Mamas A. Mamas,Matthew Sperrin,Margaret C Watson,Alasdair Coutts,Katie Wilde,Christopher R Burton,Umesh T. Kadam,Chun Shing Kwok,Chun Shing Kwok,Allan Clark,Peter Murchie,Iain Buchan,Philip C Hannaford,Phyo K. Myint +14 more
TL;DR: This study was designed to evaluate whether survival rates in patients with heart failure are better than those in Patients with diagnoses of the four most common cancers in men and women in a contemporary primary care cohort in the community in Scotland.
References
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Contribution of Primary Care to Health Systems and Health
TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities
TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys
TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article
Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary
TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.
TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.