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Journal ArticleDOI

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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Obesity in the geriatric population - a global health perspective.

TL;DR: The obesity epidemic in both developed and developing countries is described, as well as current surveillance efforts to monitor geriatric obesity on a global scale such as the Study on Global Ageing and Adult Health (SAGE study), which evaluates epidemiology trends in six different countries.
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Acute kidney injury in the community: why primary care has an important role.

TL;DR: There is mounting evidence that awareness of kidney function is central to the delivery of safe and clinically-effective care, in terms of preventing both cardiovascular events, and progression to established renal failure, with significant impacts on quality of life and healthcare expenditure.
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Global health care use by patients with type-2 diabetes: Does the type of comorbidity matter?

TL;DR: In patients with type-2 diabetes, the coexistence of mental comorbidity significantly increases the use of unplanned hospital services, and discordantComorbidities have an important effect on specialised care use.
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Implantable biomaterial based on click chemistry for targeting small molecules.

TL;DR: An implantable biomaterial is presented that harnesses in vivo click chemistry to enhance the delivery of suitable small molecules by an order of magnitude and provides the ability to precisely control the moment when biochemical and/or physical signals may appear in an implanted biomaterial.
References
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Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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