Journal ArticleDOI
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
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The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.About:
This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.read more
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Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study.
Andrew Clark,Mark Jit,Charlotte Warren-Gash,Bruce Guthrie,Harry H.X. Wang,Stewart W Mercer,Colin Sanderson,Martin McKee,Christopher Troeger,Kanyin L Ong,Francesco Checchi,Pablo Perel,Sarah Joseph,Hamish Gibbs,Amitava Banerjee,Rosalind M Eggo,Emily Nightingale,Kathleen M. O’Reilly,Thibaut Jombart,W. John Edmunds,Alicia Rosello,Fiona Yueqian Sun,Katherine E. Atkins,Nikos I Bosse,Samuel Clifford,Timothy W Russell,Arminder K Deol,Yang Liu,Simon R Procter,Quentin J Leclerc,Graham F. Medley,Gwen Knight,James D Munday,Adam J. Kucharski,Carl A. B. Pearson,Petra Klepac,Kiesha Prem,Rein M G J Houben,Akira Endo,Stefan Flasche,Nicholas G Davies,Charlie Diamond,Kevin van Zandvoort,Sebastian Funk,Megan Auzenbergs,Eleanor M Rees,Damien C. Tully,Jon C Emery,Billy J Quilty,Sam Abbott,Ch. Julián Villabona-Arenas,Stéphane Hué,Joel Hellewell,Amy Gimma,Christopher I Jarvis +54 more
TL;DR: These estimates provide a starting point for considering the number of individuals that might need to be shielded or vaccinated as the global pandemic unfolds, and focus on underlying conditions rather than other risk factors such as ethnicity, socioeconomic deprivation, and obesity.
Journal ArticleDOI
Comprehensive geriatric assessment for older adults admitted to hospital
Graham Ellis,Michael P. Gardner,Apostolos Tsiachristas,Peter Langhorne,Orlaith Burke,Rowan H. Harwood,Simon Conroy,Tilo Kircher,Dominique Somme,Ingvild Saltvedt,Heidi L. Wald,Desmond O'Neill,David Robinson,Sasha Shepperd +13 more
TL;DR: This update of a previously published Cochrane review sought to critically appraise and summarise current evidence on the effectiveness and resource use of CGA for older adults admitted to hospital, and to estimate its cost-effectiveness.
Journal ArticleDOI
The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness
Joseph Firth,Joseph Firth,Joseph Firth,Najma Siddiqi,Ai Koyanagi,Ai Koyanagi,Ai Koyanagi,Dan Siskind,Simon Rosenbaum,Cherrie Galletly,Stephanie Allan,Constanza Caneo,Rebekah Carney,André F. Carvalho,André F. Carvalho,Mary Lou Chatterton,Christoph U. Correll,Christoph U. Correll,Jackie Curtis,Fiona Gaughran,Fiona Gaughran,Adrian H. Heald,Adrian H. Heald,Adrian H. Heald,Erin Hoare,Sarah E Jackson,Steve Kisely,Steve Kisely,Karina Lovell,Mario Maj,Patrick D. McGorry,Cathrine Mihalopoulos,Hannah Myles,Brian O'Donoghue,Toby Pillinger,Jerome Sarris,Jerome Sarris,Felipe Barreto Schuch,David Shiers,Lee Smith,Marco Solmi,Shuichi Suetani,Shuichi Suetani,Johanna Taylor,Scott B Teasdale,Graham Thornicroft,John Torous,Tim Usherwood,Tim Usherwood,Davy Vancampfort,Nicola Veronese,Philip B. Ward,Alison R. Yung,Alison R. Yung,Eoin Killackey,Brendon Stubbs,Brendon Stubbs +56 more
TL;DR: This Commission summarises advances in understanding on the topic of physical health in people with mental illness, and presents clear directions for health promotion, clinical care, and future research.
Journal ArticleDOI
Clusters of Comorbidities Based on Validated Objective Measurements and Systemic Inflammation in Patients with Chronic Obstructive Pulmonary Disease
Lowie E.G.W. Vanfleteren,Martijn A. Spruit,Miriam T.J. Groenen,Swetlana Gaffron,Vanessa P. M. van Empel,Piet L.B. Bruijnzeel,Erica P.A. Rutten,Jos op 't Roodt,Emiel F.M. Wouters,Frits M.E. Franssen +9 more
TL;DR: Multimorbidity is common in patients with COPD, and different comorbidite clusters can be identified, and low-grade systemic inflammation is mostly comparable among comor bidities.
Journal ArticleDOI
Interventions to improve the appropriate use of polypharmacy for older people
Susan Patterson,Cathal A. Cadogan,Ngaire Kerse,Christopher Cardwell,Marie C. Bradley,Cristín Ryan,Carmel Hughes +6 more
TL;DR: It is unclear whether interventions to improve appropriate polypharmacy, such as pharmaceutical care, resulted in clinically significant improvement; however, they appear beneficial in terms of reducing inappropriate prescribing.
References
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Contribution of Primary Care to Health Systems and Health
TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities
TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys
TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article
Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary
TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
Journal ArticleDOI
Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.
TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.