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Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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The gap in postoperative outcome between older and younger patients with stage I-III colorectal cancer has been bridged; results from the Netherlands cancer registry.

TL;DR: Differences in postoperative mortality between older and younger CRC patients decreased between 2005 and 2016, and one-year postoperative RS was almost equal for Older and younger patients in 2015-2016.
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The burden of comorbidities in pulmonary arterial hypertension

TL;DR: The comorbidities discussed in this review (systemic hypertension, obesity, sleep apnoea, clinical depression, obstructive airway disease, thyroid disease, diabetes, and ischaemic cardiovascular event) were chosen based on their prevalence in patients with idiopathic PAH in the REVEAL registry.
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Mapping of global scientific research in comorbidity and multimorbidity: A cross-sectional analysis.

TL;DR: This study aimed to map global scientific research in comorbidity and multimorbidality to understand the maturity and growth of the area during the past decades, and is the first analysis of global scientificResearch inComorbidities and multi-bidity.
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Mental and physical health conditions in people with intellectual disabilities: Comparing local and national data

TL;DR: Further increased risk of mental disorders in an inner London borough compared to national data aligns with existing literature that highlights the negative impact of socio-economic deprivation on mental and physical health.
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Multimorbidity patterns and their relationship to mortality in the US older adult population.

TL;DR: In this article, a cross-sectional study with longitudinal mortality follow-up employed latent class analysis (LCA) to develop clinically meaningful subgroups of participants aged 50 and older with different combinations of 13 chronic conditions from the National Health Interview Survey 2002-2014.
References
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Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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