Journal ArticleDOI
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.About:
This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.read more
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A 12-year retrospective analysis of differences between elderly and oldest old patients referred to the emergency department of a large tertiary hospital.
Marcello Covino,C. Petruzziello,Graziano Onder,Alessio Migneco,Benedetta Simeoni,Francesco Franceschi,Veronica Ojetti +6 more
TL;DR: The number of attendances at the authors' ED by elderly patients in the 12 years from January 2005 to December 2017 is evaluated to reduce hospitalization in the elderly, avoiding disruption to the home care of people with dementia, and reducing both the risk of falls and hospital infections.
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Evidence-based design recommendations for prevalence studies on multimorbidity: improving comparability of estimates
TL;DR: Comparable prevalence estimates are urgently needed for realistic description of the magnitude of the problem of multimorbidity and design recommendations are made based on the results of analyses of variables affecting prevMM.
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Transforming the future of ageing
Jean-Pierre Michel,Diana Kuh,Rose Anne Kenny,Richard B. Reilly,Liat Ayalon,Axel H. Boersch-Supan,Jacques Bringer,Alfonso José Cruz Jentoft,Giovanni Gambassi,Alan J. Gow,Tomasz Grodzicki,Lenka Lhotska,Ekaterina L. Markova,Rytis Maskeliunas,Carlo Patrono,Lene Juel Rasmussen,Regina Roller-Wirnsberger,Archana Singh-Manoux,P. Eline Slagboom,Anne Pieter van der Mei,Leo van Wissen,Jose Viña +21 more
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Computational analysis of multimorbidity between asthma, eczema and rhinitis
Daniel Aguilar,Mariona Pinart,Gerard H. Koppelman,Yvan Saeys,Martijn C. Nawijn,Dirkje S. Postma,M. Akdis,Charles Auffray,Stephane Ballereau,Marta Benet,Judith Garcia-Aymerich,Juan R. González,Stefano Guerra,Thomas Keil,Manolis Kogevinas,Bart N. Lambrecht,Nathanaël Lemonnier,Erik Melén,Jordi Sunyer,Rudolf Valenta,Sergi Valverde,Magnus Wickman,Jean Bousquet,Jean Bousquet,Baldo Oliva,Josep M. Antó +25 more
TL;DR: Asthma, eczema and rhinitis shared a larger number of associated proteins than expected by chance, and their associated proteins exhibited a significant degree of interconnectedness in the interaction network, suggesting that type 2 signaling pathways represent a relevant multimorbidity mechanism of allergic diseases.
Journal ArticleDOI
The Hotel Study—Clinical and Health Service Effectiveness in a Cohort of Homeless or Marginally Housed Persons:
William G. Honer,Alejandro Cervantes-Larios,Andrea A. Jones,Fidel Vila-Rodriguez,Julio S. G. Montaner,Howard Tran,Jimmy Nham,William J. Panenka,Donna J. Lang,Allen E. Thornton,Talia Vertinsky,Alasdair M. Barr,Ric M. Procyshyn,Geoffrey N. Smith,Tari Buchanan,Mel Krajden,Michael Krausz,G. William MacEwan,Kristina M. Gicas,Olga Leonova,Verena Langheimer,Alexander Rauscher,Krista Schultz +22 more
TL;DR: Mapping confirmed the association between poverty and greater number of emergency visits related to substance use and mental illness and assessed the clinical effectiveness of existing, illness-specific treatment strategies and health care delivery for multimorbid illnesses.
References
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Contribution of Primary Care to Health Systems and Health
TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities
TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys
TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article
Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary
TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.
TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.