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Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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Multimorbidity of cardiometabolic diseases: prevalence and risk for mortality from one million Chinese adults in a longitudinal cohort study

TL;DR: The prevalence of cardiometabolic multimorbidity in a general Chinese population increased more than doubled over 5 years, indicating rapid evolution of cardiological diseases.
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Reducing emergency admissions through community based interventions

TL;DR: Evidence for current interventions is limited and the alternatives are limited, so Emma Wallace and colleagues discuss the alternatives.
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Trends in multimorbidity and polypharmacy in the Flemish-Belgian population between 2000 and 2015.

TL;DR: For all adult age groups multimorbidity and polypharmacy are frequent, dynamic over time and increasing, and asks for both epidemiological and interventional studies to improve the management of the resulting complex care.
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A systematic review of the outcomes reported in trials of medication review in older patients: the need for a core outcome set.

TL;DR: Outcome reporting from RCTs concerning medication review in older patients is heterogeneous, highlighting the need for a standardized core outcome set for medication review for older patients, to improve outcome reporting and evidence synthesis.
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Why do patients with multimorbidity in England report worse experiences in primary care? Evidence from the General Practice Patient Survey

TL;DR: Patient-centred measures of health-related quality of life, especially pain, are more important than the number of conditions in explaining why patients with multiple long-term conditions report worse experiences of care.
References
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Journal ArticleDOI

Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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