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Journal ArticleDOI

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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Risk of developing multimorbidity across all ages in an historical cohort study: differences by sex and ethnicity.

TL;DR: The risk of developing de novo multimorbidity increases steeply with older age, varies by ethnicity and is similar in men and women overall, however, the combinations of conditions vary extensively by age and sex.
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Senescence in COPD and Its Comorbidities.

TL;DR: COPD is associated with several comorbidities (multimorbidity), such as cardiovascular and metabolic diseases, that share the same pathways of accelerated aging.
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Clinical assessment and management of multimorbidity: summary of NICE guidance

TL;DR: This guideline is intended to provide guidance on the optimum management of people with multimorbidity who need an approach to care which is largely based on trials of interventions for single conditions, from which people with multi-million dollar conditions are often excluded.
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Effectiveness of Case Management for 'At Risk' Patients in Primary Care: A Systematic Review and Meta-Analysis

TL;DR: Current results do not support case management as an effective model, especially concerning reduction of secondary care use or total costs, and reasons for lack of effect are considered.
References
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Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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