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Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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Impact and cost-effectiveness of a universal strategy to promote physical activity in primary care: population-based cohort study and Markov model

TL;DR: A universal strategy to promote physical activity in primary care has the potential to increase life years lived free from physical disease and there is only weak evidence that a universal intervention strategy might prove cost-effective.
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Acute and chronic diseases as part of multimorbidity in acutely hospitalized older patients

TL;DR: There is a need for strategies addressing multimorbidity during the exacerbation of chronic diseases, and specific associations between acute and chronic diseases are identified.
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Modelling successful primary care for multimorbidity: a realist synthesis of successes and failures in concurrent learning and healthcare delivery

TL;DR: This study asked ‘what is known about how and why concurrent healthcare delivery and professional experiential learning interact to generate outcomes, valued by patients, general practitioners and trainees, for patients with multimorbidity in primary care?’
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The association between multimorbidity and poor adherence with cardiovascular medications

TL;DR: Using medication adherence as the outcome variable, multimorbidity was significantly associated with poor drug adherence and implies the need for closer monitoring of the medication taking behavior among those with multiple chronic conditions.
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Mortality of Older Patients Admitted to an ICU: A Systematic Review.

TL;DR: Substantial variation in short- and long-term mortality as well as in prognostic factors evaluated is documented, requiring consistent, high-quality data on pre-ICU conditions, ICU physiology and treatments, structure and system factors, and post- ICU trajectories to better understand this variation.
References
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Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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