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Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

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TLDR
The findings challenge the single-disease framework by which most health care, medical research, and medical education is configured, and a complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas.
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This article is published in The Lancet.The article was published on 2012-07-07. It has received 4839 citations till now. The article focuses on the topics: Comorbidity & Health services research.

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Oral health for an ageing population: the importance of a natural dentition in older adults

TL;DR: There is an overwhelming body of evidence that maintaining a healthy natural dentition in old age is beneficial from a structural, functional and psycho-social point of view.
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The role of physical activity in the relationship between self-perceptions of ageing and self-rated health in older adults.

TL;DR: Having more positive self-perceptions of ageing is associated with higher levels of physical activity, which in turn predict better self-rated health over time, which supports the hypothesis of a behavioural pathway in the self- perceptive of ageing – health link.
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The Prevalence of Chronic Conditions and Poor Health Among People With and Without Vision Impairment, Aged ≥65 Years, 2010–2014

TL;DR: Higher prevalence of chronic conditions is strongly associated with vision impairment among the older people and poor health is strongly related to vision impairment and chronic conditions.
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Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan.

TL;DR: How humans’ pace of biological aging relates to personal‐history characteristics is reported to inform clinical trials about this heterogeneity, and how trials of anti‐aging therapies will need to ascertain personal histories retrospectively is replicated.
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Cardiac effects of current treatments of chronic obstructive pulmonary disease

TL;DR: The difficulties of, and pitfalls in, the investigation of the safety of drug treatments in COPD are reported; potential warnings about rare cardiac events caused by COPD treatment need to be confirmed in high quality large randomised controlled trials.
References
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Contribution of Primary Care to Health Systems and Health

TL;DR: The means by which primary care improves health have been identified, thus suggesting ways to improve overall health and reduce differences in health across major population subgroups.
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Social determinants of health inequalities

TL;DR: A Commission on Social Determinants of Health is launching, which will review the evidence, raise societal debate, and recommend policies with the goal of improving health of the world's most vulnerable people.
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Depression, chronic diseases, and decrements in health: results from the World Health Surveys

TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article

Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary

TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.
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Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance.

TL;DR: It is suggested that adhering to current CPGs in caring for an older person with several comorbidities may have undesirable effects and could create perverse incentives that emphasize the wrong aspects of care for this population and diminish the quality of their care.
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