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Open AccessJournal ArticleDOI

Extinction Learning in Humans: Role of the Amygdala and vmPFC

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TLDR
The neural mechanisms of fear extinction in humans are explored and activation in the vmPFC was primarily linked to the expression of fear learning during a delayed test of extinction, indicating that the mechanisms of extinction learning may be preserved across species.
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This article is published in Neuron.The article was published on 2004-09-16 and is currently open access. It has received 1557 citations till now. The article focuses on the topics: Extinction (psychology).

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The cognitive control of emotion.

TL;DR: The results suggest a functional architecture for the cognitive control of emotion that dovetails with findings from other human and nonhuman research on emotion.
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Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia

TL;DR: A meta-analysis of functional magnetic resonance imaging and positron emission tomography studies of posttraumatic stress disorder, social anxiety disorder, specific phobia, and fear conditioning in healthy individuals provided neuroimaging evidence for common brain mechanisms in anxiety disorders and normal fear.
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Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior

TL;DR: Five major research topics are highlighted that illustrate parallel roles for the amygdala in humans and other animals, including implicit emotional learning and memory, emotional modulation of memory,otional influences on attention and perception, emotion and social behavior, and emotion inhibition and regulation.
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Emotional processing in anterior cingulate and medial prefrontal cortex

TL;DR: A wealth of recent research on negative emotions in animals and humans is examined, and it is concluded that, contrary to the traditional dichotomy, both subdivisions make key contributions to emotional processing.
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The integration of negative affect, pain and cognitive control in the cingulate cortex

TL;DR: It is demonstrated that negative affect, pain and cognitive control activate an overlapping region of the dorsal cingulate — the anterior midcingulate cortex (aMCC), which constitutes a hub where information about reinforcers can be linked to motor centres responsible for expressing affect and executing goal-directed behaviour.
References
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Searching for a baseline: Functional imaging and the resting human brain

TL;DR: This work explores the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations, including the manner in which a baseline is defined and the implications of such a baseline for the understanding ofbrain function.
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Storage and executive processes in the frontal lobes.

TL;DR: The human frontal cortex helps mediate working memory, a system that is used for temporary storage and manipulation of information and that is involved in many higher cognitive functions.
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Subgenual prefrontal cortex abnormalities in mood disorders

TL;DR: Using positron emission tomographic images of cerebral blood flow and rate of glucose metabolism to measure brain activity, an area of abnormally decreased activity is localized in the pre-frontal cortex ventral to the genu of the corpus callosum in both familial bipolar depressives and familial unipolar depressives.
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Rethinking Feelings: An fMRI Study of the Cognitive Regulation of Emotion

TL;DR: Functional magnetic resonance imaging findings support the hypothesis that prefrontal cortex is involved in constructing reappraisal strategies that can modulate activity in multiple emotion-processing systems.
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