Fast Virtual Fractional Flow Reserve Based Upon Steady-State Computational Fluid Dynamics Analysis: Results From the VIRTU-Fast Study
Paul Morris,Paul Morris,Daniel Alejandro Silva Soto,Jeroen F.A. Feher,D. Rafiroiu,Angela Lungu,Susheel Varma,Patricia V. Lawford,D. Rodney Hose,Julian Gunn,Julian Gunn +10 more
TLDR
In this article, two mathematical methods (steady and pseudotransient) were developed that accelerate the computation of vFFR from >36h to <36h using paired steady-state CFD analyses, without the need for computationally expensive, full transient CFD analysis.About:
This article is published in JACC: Basic to Translational Science.The article was published on 2017-08-01 and is currently open access. It has received 75 citations till now.read more
Citations
More filters
Journal ArticleDOI
Diagnostic Performance of In‐Procedure Angiography‐Derived Quantitative Flow Reserve Compared to Pressure‐Derived Fractional Flow Reserve: The FAVOR II Europe‐Japan Study
Jelmer Westra,Birgitte Krogsgaard Andersen,Gianluca Campo,Hitoshi Matsuo,Lukasz Koltowski,Ashkan Eftekhari,Tommy Liu,Luigi Di Serafino,Domenico Di Girolamo,Javier Escaned,Holger Nef,Christoph Naber,Marco Barbierato,Shengxian Tu,Omeed Neghabat,Morten Madsen,Matteo Tebaldi,Toru Tanigaki,Janusz Kochman,Samer Somi,Giovanni Esposito,Giuseppe Mercone,Hernán Mejía-Rentería,Federico Ronco,Hans Erik Bøtker,William Wijns,Evald Høj Christiansen,Niels Ramsing Holm +27 more
TL;DR: Online computation of QFR in the catheterization laboratory is clinically feasible and is superior to angiographic assessment for evaluation of intermediary coronary artery stenosis using FFR as a reference standard.
Journal ArticleDOI
Accuracy of Fractional Flow Reserve Derived From Coronary Angiography
William F. Fearon,Stephan Achenbach,Thomas Engstrøm,Abid Assali,Richard Shlofmitz,Allen Jeremias,Stephane Fournier,Ajay J. Kirtane,Ran Kornowski,Gabriel Greenberg,Rami Jubeh,Daniel M. Kolansky,Thomas McAndrew,Ovidiu Dressler,Akiko Maehara,Mitsuaki Matsumura,Martin B. Leon,Bernard De Bruyne +17 more
TL;DR: FFRangio measured from the coronary angiogram alone has a high sensitivity, specificity, and accuracy compared with pressure wire–derived FFR, and has the promise to substantially increase physiological coronary lesion assessment in the catheterization laboratory, thereby potentially leading to improved patient outcomes.
Journal ArticleDOI
Fractional flow reserve in clinical practice: from wire-based invasive measurement to image-based computation
Shengxian Tu,Jelmer Westra,Julien Adjedj,Daixin Ding,Fuyou Liang,Bo Xu,Niels Ramsing Holm,Johan H. C. Reiber,William Wijns +8 more
TL;DR: Computational FFR has the potential to expand and facilitate the use of physiology for diagnosis, procedural guidance, and evaluation of therapies, with anticipated impact on resource utilization and patient outcomes.
Journal ArticleDOI
Accuracy of computational pressure-fluid dynamics applied to coronary angiography to derive fractional flow reserve: FLASH FFR
Jianping Li,Yanjun Gong,Weimin Wang,Qing Yang,Bin Liu,Yuan Lu,Yawei Xu,Yunlong Huo,Yi Tieci,Jian Liu,Yongle Li,Shaopeng Xu,Lei Zhao,Ziad A. Ali,Ziad A. Ali,Yong Huo +15 more
TL;DR: Using wire-based FFR as the reference, caFFR has high accuracy, sensitivity and specificity and could eliminate the need of a pressure wire, technical error and potentially increase adoption of physiological assessment of coronary artery stenosis severity.
Journal ArticleDOI
Comparison of 1D and 3D Models for the Estimation of Fractional Flow Reserve
Pablo J. Blanco,Carlos A. Bulant,Lucas O. Müller,G. D. Maso Talou,C. Guedes Bezerra,Pedro A. Lemos,Raúl A. Feijóo +6 more
TL;DR: In this paper, the predictive capabilities of one-dimensional (1D) blood flow models with full 3D models in the context of patient-specific coronary hemodynamics in hyperemic conditions were validated.
References
More filters
Journal ArticleDOI
Statistical methods for assessing agreement between two methods of clinical measurement.
TL;DR: An alternative approach, based on graphical techniques and simple calculations, is described, together with the relation between this analysis and the assessment of repeatability.
Journal ArticleDOI
Statistical methods for assessing agreement between two methods of clinical measurement
TL;DR: In this article, an alternative approach, based on graphical techniques and simple calculations, is described, together with the relation between this analysis and the assessment of repeatability, which is often used in clinical comparison of a new measurement technique with an established one.
Journal ArticleDOI
Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates
TL;DR: In this article, global sensitivity indices for rather complex mathematical models can be efficiently computed by Monte Carlo (or quasi-Monte Carlo) methods, which are used for estimating the influence of individual variables or groups of variables on the model output.
Journal ArticleDOI
Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)
William Wijns,Philippe Kolh,Nicolas Danchin,Volkmar Falk,Stefan James,Miodrag Ostojic,Massimo F. Piepoli,Charles Pirlet,José L. Pomar,Flavio Ribichini,Martin J. Schalij,Paul Sergeant,Patrick W. Serruys,Sigmund Silber,David P. Taggart +14 more
TL;DR: Guidelines and Expert Consensus Documents summarize and evaluate all available evidence to assist physicians in selecting the best management strategy for an individual patient suffering from a given condition, taking into account the impact on outcome and the risk–benefit ratio of diagnostic or therapeutic means.
Related Papers (5)
Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease
Bernard De Bruyne,Bindu Kalesan,Emanuele Barbato,Zsolt Piroth,Nikola Jagic,Sven Mobius-Winckler,Gilles Rioufol,Nils Witt,Petr Kala,Philip MacCarthy,Thomas Engstrøm,Keith G. Oldroyd,Kreton Mavromatis,Ganesh Manoharan,Peter Verlee,Ole Fröbert,Nick Curzen,Jane B. Johnson,Peter Jüni,William F. Fearon,Trial Investigators +20 more